public string CalculateMetricDose(Patient patient, string courseId, string planId, string structureId, PQMViewModel objective)
{
var plan = Extensions.GetPlanningItem(patient, courseId, planId);
var planVM = new PlanningItemViewModel(plan);
var structure = Extensions.GetStructure(plan, structureId);
DirectoryInfo constraintDir = new DirectoryInfo(Path.Combine(AssemblyHelper.GetAssemblyDirectory(), "ConstraintTemplates"));
string firstFileName = constraintDir.GetFiles().FirstOrDefault().ToString();
string firstConstraintFilePath = Path.Combine(constraintDir.ToString(), firstFileName);
// make sure the workbook template exists
if (!System.IO.File.Exists(firstConstraintFilePath))
{
System.Windows.MessageBox.Show(string.Format("The template file '{0}' chosen does not exist.", firstConstraintFilePath));
}
var structureVM = new StructureViewModel(structure);
string metric = "";
var goal = "";
string result = "";
string variation = "";
if (objective.TemplateId == structureId)
{
metric = objective.DVHObjective;
goal = objective.Goal;
variation = objective.Variation;
result = _metricCalc.CalculateMetric(planVM.PlanningItemStructureSet, structureVM, planVM, metric);
}
else
{
result = "";
}
return(result);
}
public StructureSetViewModel(StructureSet structureSet)
{
var StructureList = new ObservableCollection <StructureViewModel>();
foreach (Structure structure in structureSet.Structures)
{
if (!structure.IsEmpty && structure.DicomType != "SUPPORT")
{
var structureViewModel = new StructureViewModel(structure);
StructureList.Add(structureViewModel);
}
}
StructureList = new ObservableCollection <StructureViewModel>(StructureList.OrderBy(x => x.StructureId));
}
public static string GetCoveredDoseAtVolume(StructureSet structureSet, PlanningItemViewModel planningItem, StructureViewModel evalStructure, MatchCollection testMatch, Group evalunit)
{
System.Console.WriteLine("Covered Dose at Volume");
return("Not supported");
}
public static string GetMinMaxMean(StructureSet structureSet, PlanningItemViewModel planningItem, StructureViewModel evalStructure, MatchCollection testMatch, Group evalunit, Group type)
{
if (type.Value.CompareTo("Volume") == 0)
{
return(string.Format("{0:0.00} {1}", evalStructure.Structure.Volume, evalunit.Value));
}
else
{
double planSumRxDose = 0;
DVHData dvh;
DoseValuePresentation dvp = (evalunit.Value.CompareTo("%") == 0) ? DoseValuePresentation.Relative : DoseValuePresentation.Absolute;
if (dvp == DoseValuePresentation.Relative && planningItem.PlanningItemObject is PlanSum)
{
PlanSum planSum = (PlanSum)planningItem.PlanningItemObject;
foreach (PlanSetup planSetup in planSum.PlanSetups)
{
double planSetupRxDose = planSetup.TotalDose.Dose;
planSumRxDose += planSetupRxDose;
}
dvh = planningItem.PlanningItemObject.GetDVHCumulativeData(evalStructure.Structure, DoseValuePresentation.Absolute, VolumePresentation.Relative, 0.1);
}
else
{
dvh = planningItem.PlanningItemObject.GetDVHCumulativeData(evalStructure.Structure, dvp, VolumePresentation.Relative, 0.1);
}
if (type.Value.CompareTo("Max") == 0)
{
//checking dose output unit and adapting to template
//Gy to cGy
if ((evalunit.Value.CompareTo("Gy") == 0) && (dvh.MaxDose.Unit.CompareTo(DoseValue.DoseUnit.cGy) == 0))
{
return(new DoseValue(dvh.MaxDose.Dose / 100, DoseValue.DoseUnit.Gy).ToString());
}
//Gy to Gy or % to %
else
{
if (dvp == DoseValuePresentation.Relative && planningItem.PlanningItemObject is PlanSum)
{
double maxDoseDouble = double.Parse(dvh.MaxDose.ValueAsString);
//double
return((maxDoseDouble / planSumRxDose * 100).ToString("0.0") + " " + evalunit.Value);
}
else
{
return(dvh.MaxDose.ToString());
}
}
}
else if (type.Value.CompareTo("Min") == 0)
{
//checking dose output unit and adapting to template
//Gy to cGy
if ((evalunit.Value.CompareTo("Gy") == 0) && (dvh.MinDose.Unit.CompareTo(DoseValue.DoseUnit.cGy) == 0))
{
return(new DoseValue(dvh.MinDose.Dose / 100, DoseValue.DoseUnit.Gy).ToString());
}
//Gy to Gy or % to %
else
{
return(dvh.MinDose.ToString());
}
}
else
{
//checking dose output unit and adapting to template
//Gy to cGy
if ((evalunit.Value.CompareTo("Gy") == 0) && (dvh.MeanDose.Unit.CompareTo(DoseValue.DoseUnit.cGy) == 0))
{
return(new DoseValue(dvh.MeanDose.Dose / 100, DoseValue.DoseUnit.Gy).ToString());
}
//Gy to Gy or % to %
else
{
return(dvh.MeanDose.ToString());
}
}
}
}
public static string GetCoveredVolumeAtDose(StructureSet structureSet, PlanningItemViewModel planningItem, StructureViewModel evalStructure, MatchCollection testMatch, Group evalunit)
{
//check for sufficient sampling and dose coverage
DVHData dvh = planningItem.PlanningItemObject.GetDVHCumulativeData(evalStructure.Structure, DoseValuePresentation.Absolute, VolumePresentation.Relative, 0.1);
if ((dvh.SamplingCoverage < 0.9) || (dvh.Coverage < 0.9))
{
return("Unable to calculate - insufficient dose or sampling coverage");
}
Group eval = testMatch[0].Groups["evalpt"];
Group unit = testMatch[0].Groups["unit"];
DoseValue.DoseUnit du = (unit.Value.CompareTo("%") == 0) ? DoseValue.DoseUnit.Percent :
(unit.Value.CompareTo("cGy") == 0) ? DoseValue.DoseUnit.cGy : DoseValue.DoseUnit.Unknown;
VolumePresentation vp = (unit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
DoseValue dv = new DoseValue(double.Parse(eval.Value), du);
double volume = double.Parse(eval.Value);
VolumePresentation vpFinal = (evalunit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
DoseValuePresentation dvpFinal = (evalunit.Value.CompareTo("%") == 0) ? DoseValuePresentation.Relative : DoseValuePresentation.Absolute;
double volumeAchieved = planningItem.PlanningItemObject.GetVolumeAtDose(evalStructure.Structure, dv, vpFinal);
double organVolume = evalStructure.Structure.Volume;
double coveredVolume = organVolume - volumeAchieved;
return(string.Format("{0:0.00} {1}", coveredVolume, evalunit.Value)); // todo: better formatting based on VolumePresentation
}
public static string GetVolumeAtDose(StructureSet structureSet, PlanningItemViewModel planningItem, StructureViewModel evalStructure, MatchCollection testMatch, Group evalunit)
{
//check for sufficient sampling and dose coverage
DVHData dvh = planningItem.PlanningItemObject.GetDVHCumulativeData(evalStructure.Structure, DoseValuePresentation.Absolute, VolumePresentation.Relative, 0.1);
//MessageBox.Show(evalStructure.Id + "- Eval unit: " + evalunit.Value.ToString() + "Achieved unit: " + dvAchieved.UnitAsString + " - Sampling coverage: " + dvh.SamplingCoverage.ToString() + " Coverage: " + dvh.Coverage.ToString());
if ((dvh.SamplingCoverage < 0.9) || (dvh.Coverage < 0.9))
{
return("Unable to calculate - insufficient dose or sampling coverage");
}
Group eval = testMatch[0].Groups["evalpt"];
Group unit = testMatch[0].Groups["unit"];
DoseValue.DoseUnit du = (unit.Value.CompareTo("%") == 0) ? DoseValue.DoseUnit.Percent :
(unit.Value.CompareTo("cGy") == 0) ? DoseValue.DoseUnit.cGy : DoseValue.DoseUnit.Unknown;
VolumePresentation vp = (unit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
DoseValue dv = new DoseValue(double.Parse(eval.Value), du);
double volume = double.Parse(eval.Value);
VolumePresentation vpFinal = (evalunit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
DoseValuePresentation dvpFinal = (evalunit.Value.CompareTo("%") == 0) ? DoseValuePresentation.Relative : DoseValuePresentation.Absolute;
if (planningItem.PlanningItemObject is PlanSum)
{
double planDoseDouble = 0;
PlanSum planSum = (PlanSum)planningItem.PlanningItemObject;
foreach (PlanSetup planSetup in planSum.PlanSetups)
{
planDoseDouble += planSetup.TotalDose.Dose;
}
dv = new DoseValue(planDoseDouble, DoseValue.DoseUnit.cGy);
}
double volumeAchieved = planningItem.PlanningItemObject.GetVolumeAtDose(evalStructure.Structure, dv, vpFinal);
return(string.Format("{0:0.00} {1}", volumeAchieved, evalunit.Value)); // todo: better formatting based on VolumePresentation
//#if false
// string message = string.Format("{0} - Dose unit = {1}, Volume Presentation = {2}, vpFinal = {3}, dvpFinal ={4}",
// objective.DVHObjective, du.ToString(), vp.ToString(), vpFinal.ToString(), dvpFinal.ToString());
// MessageBox.Show(message);
//#endif
}
public static string GetDoseAtVolume(StructureSet structureSet, PlanningItemViewModel planningItem, StructureViewModel evalStructure, MatchCollection testMatch, Group evalunit)
{
//check for sufficient dose and sampling coverage
DVHData dvh = planningItem.PlanningItemObject.GetDVHCumulativeData(evalStructure.Structure, DoseValuePresentation.Absolute, VolumePresentation.Relative, 0.1);
if (dvh != null)
{
if ((dvh.SamplingCoverage < 0.9) || (dvh.Coverage < 0.9))
{
return("Unable to calculate - insufficient dose or sampling coverage");
}
Group eval = testMatch[0].Groups["evalpt"];
Group unit = testMatch[0].Groups["unit"];
DoseValue.DoseUnit du = (unit.Value.CompareTo("%") == 0) ? DoseValue.DoseUnit.Percent :
(unit.Value.CompareTo("cGy") == 0) ? DoseValue.DoseUnit.cGy : DoseValue.DoseUnit.Unknown;
VolumePresentation vp = (unit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
DoseValue dv = new DoseValue(double.Parse(eval.Value), du);
double volume = double.Parse(eval.Value);
VolumePresentation vpFinal = (evalunit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
DoseValuePresentation dvpFinal = (evalunit.Value.CompareTo("%") == 0) ? DoseValuePresentation.Relative : DoseValuePresentation.Absolute;
DoseValue dvAchieved = planningItem.PlanningItemObject.GetDoseAtVolume(evalStructure.Structure, volume, vp, dvpFinal);
//checking dose output unit and adapting to template
if (dvAchieved.UnitAsString.CompareTo(evalunit.Value.ToString()) != 0)
{
if ((evalunit.Value.CompareTo("cGy") == 0) && (dvAchieved.Unit.CompareTo(DoseValue.DoseUnit.cGy) == 0))
{
dvAchieved = new DoseValue(dvAchieved.Dose / 100, DoseValue.DoseUnit.cGy);
}
else
{
return("Unable to calculate");
}
}
return(dvAchieved.ToString());
}
else
{
return("Unable to calculate - structure is empty");
}
}
public static string GetConformationNumber(StructureSet structureSet, PlanningItemViewModel planningItem, StructureViewModel evalStructure, MatchCollection testMatch, Group evalunit)
{
DVHData dvh = planningItem.PlanningItemObject.GetDVHCumulativeData(evalStructure.Structure, DoseValuePresentation.Absolute, VolumePresentation.Relative, 0.1);
DoseValue prescribedDose;
double planDoseDouble = 0;
if ((dvh.SamplingCoverage < 0.9) || (dvh.Coverage < 0.9))
{
return("Unable to calculate - insufficient dose or sampling coverage");
}
if (planningItem.PlanningItemObject is PlanSum)
{
PlanSum planSum = (PlanSum)planningItem.PlanningItemObject;
foreach (PlanSetup planSetup in planSum.PlanSetups)
{
planDoseDouble += planSetup.TotalDose.Dose;
}
}
if (planningItem.PlanningItemObject is PlanSetup)
{
PlanSetup planSetup = (PlanSetup)planningItem.PlanningItemObject;
planDoseDouble = planSetup.TotalDose.Dose;
}
prescribedDose = new DoseValue(planDoseDouble, DoseValue.DoseUnit.cGy);
Group eval = testMatch[0].Groups["evalpt"];
Group unit = testMatch[0].Groups["unit"];
DoseValue.DoseUnit du = (unit.Value.CompareTo("%") == 0) ? DoseValue.DoseUnit.Percent :
(unit.Value.CompareTo("cGy") == 0) ? DoseValue.DoseUnit.cGy : DoseValue.DoseUnit.Unknown;
var body = structureSet.Structures.Where(x => x.Id.Contains("BODY")).First();
//VolumePresentation vpFinal = (evalunit.Value.CompareTo("%") == 0) ? VolumePresentation.Relative : VolumePresentation.AbsoluteCm3;
VolumePresentation vpFinal = VolumePresentation.AbsoluteCm3;
DoseValuePresentation dvpFinal = (evalunit.Value.CompareTo("%") == 0) ? DoseValuePresentation.Relative : DoseValuePresentation.Absolute;
DoseValue dv = new DoseValue(double.Parse(eval.Value) / 100 * prescribedDose.Dose, DoseValue.DoseUnit.cGy);
double bodyWithPrescribedDoseVolume = planningItem.PlanningItemObject.GetVolumeAtDose(body, prescribedDose, vpFinal);
double targetWithPrescribedDoseVolume = planningItem.PlanningItemObject.GetVolumeAtDose(evalStructure.Structure, dv, vpFinal);
double targetVolume = evalStructure.Structure.Volume;
var cn = (targetWithPrescribedDoseVolume / targetVolume) * (targetWithPrescribedDoseVolume / bodyWithPrescribedDoseVolume);
return(string.Format("{0:0.0}", cn));
}
public string CalculateMetric(StructureSet structureSet, StructureViewModel evalStructure, PlanningItemViewModel planningItem, string DVHObjective)
{
//start with a general regex that pulls out the metric type and the @ (evalunit) part.
string pattern = @"^(?<type>[^\[\]]+)(\[(?<evalunit>[^\[\]]+)\])$";
string minmaxmean_Pattern = @"^(M(in|ax|ean)|Volume)$"; //check for Max or Min or Mean or Volume
string d_at_v_pattern = @"^D(?<evalpt>\d+\p{P}\d+|\d+)(?<unit>(%|cc))$"; // matches D95%, D2cc
string dc_at_v_pattern = @"^DC(?<evalpt>\d+)(?<unit>(%|cc))$"; // matches DC95%, DC700cc
string v_at_d_pattern = @"^V(?<evalpt>\d+\p{P}\d+|\d+)(?<unit>(%|Gy|cGy))$"; // matches V98%, V40Gy
string cv_at_d_pattern = @"^CV(?<evalpt>\d+)(?<unit>(%|Gy|cGy))$"; // matches CV98%, CV40Gy
// Max[Gy] D95%[%] V98%[%] CV98%[%] D2cc[Gy] V40Gy[%]
string cn_pattern = @"^CN(?<evalpt>\d+\p{P}\d+|\d+)(?<unit>(%|Gy|cGy))$"; //matches CN50%
string gi_pattern = @"^GI(?<evalpt>\d+\p{P}\d+|\d+)(?<unit>(%|Gy|cGy))$"; //matches GI50%
//Structure evalStructure = ;
if (evalStructure == null)
{
return("Structure not found");
}
//start with a general regex that pulls out the metric type and the [evalunit] part.
var matches = Regex.Matches(DVHObjective, pattern);
if (matches.Count != 1)
{
return(string.Format("DVH Objective expression \"{0}\" is not a recognized expression type.", DVHObjective));
}
Match m = matches[0];
Group type = m.Groups["type"];
Group evalunit = m.Groups["evalunit"];
Console.WriteLine("expression {0} => type = {1}, unit = {2}", DVHObjective, type.Value, evalunit.Value);
// further decompose <type>
var testMatch = Regex.Matches(type.Value, minmaxmean_Pattern);
if (testMatch.Count != 1)
{
testMatch = Regex.Matches(type.Value, v_at_d_pattern);
if (testMatch.Count != 1)
{
testMatch = Regex.Matches(type.Value, d_at_v_pattern);
if (testMatch.Count != 1)
{
testMatch = Regex.Matches(type.Value, cv_at_d_pattern);
if (testMatch.Count != 1)
{
testMatch = Regex.Matches(type.Value, dc_at_v_pattern);
if (testMatch.Count != 1)
{
testMatch = Regex.Matches(type.Value, cn_pattern);
if (testMatch.Count != 1)
{
testMatch = Regex.Matches(type.Value, gi_pattern);
if (testMatch.Count != 1)
{
return(string.Format("DVH Objective expression \"{0}\" is not a recognized expression type.", DVHObjective));
}
else
{
// we have Gradient Index pattern
return(PQMGradientIndex.GetGradientIndex(structureSet, planningItem, evalStructure, testMatch, evalunit));
}
}
else
{
// we have Conformation Number pattern
return(PQMConformationNumber.GetConformationNumber(structureSet, planningItem, evalStructure, testMatch, evalunit));
}
}
else
{
// we have Covered Dose at Volume pattern
return(PQMCoveredDoseAtVolume.GetCoveredDoseAtVolume(structureSet, planningItem, evalStructure, testMatch, evalunit));
}
}
else
{
// we have Covered Volume at Dose pattern
return(PQMCoveredVolumeAtDose.GetCoveredVolumeAtDose(structureSet, planningItem, evalStructure, testMatch, evalunit));
}
}
else
{
// we have Dose at Volume pattern
return(PQMDoseAtVolume.GetDoseAtVolume(structureSet, planningItem, evalStructure, testMatch, evalunit));
}
}
else
{
// we have Volume at Dose pattern
return(PQMVolumeAtDose.GetVolumeAtDose(structureSet, planningItem, evalStructure, testMatch, evalunit));
}
}
else
{
// we have Min, Max, Mean, or Volume
return(PQMMinMaxMean.GetMinMaxMean(structureSet, planningItem, evalStructure, testMatch, evalunit, type));
}
}