/// <summary>
/// Initializes a new instance of the <see cref="DataSetViewModel"/> class.
/// </summary>
/// <param name="dialogService">A dialog service for opening dialogs from the view model</param>
public DataSetViewModel(IMainDialogService dialogService)
{
this.dialogService = dialogService;
this.ReadyToClose = false;
this.IdFileOpen = false;
this.SelectedPrSm = new PrSm();
this.ScanViewModel = new ScanViewModel(dialogService, new List <PrSm>());
this.CreateSequenceViewModel = new CreateSequenceViewModel(dialogService)
{
SelectedDataSetViewModel = this
};
this.CreateSequenceViewModel.CreateAndAddPrSmCommand.Subscribe(
_ => this.ScanViewModel.Data.Add(this.CreateSequenceViewModel.SelectedPrSm));
// Remove filter by raw file name from ScanViewModel filters
this.ScanViewModel.Filters.Remove(this.ScanViewModel.Filters.FirstOrDefault(f => f.Name == "Raw File Name"));
// When a PrSm is selected from the ScanViewModel, update the SelectedPrSm for this data set
this.ScanViewModel.WhenAnyValue(x => x.SelectedPrSm).Where(prsm => prsm != null).Subscribe(x => this.SelectedPrSm = x);
// When the scan number in the selected prsm changes, the selected scan in the xic plots should update
this.WhenAnyValue(x => x.SelectedPrSm)
.Where(_ => this.SelectedPrSm != null && this.SpectrumViewModel != null && this.XicViewModel != null)
.Subscribe(prsm =>
{
this.SpectrumViewModel.UpdateSpectra(prsm.Scan, this.SelectedPrSm.PrecursorMz);
this.XicViewModel.SetSelectedScan(prsm.Scan);
this.XicViewModel.ZoomToScan(prsm.Scan);
});
var prsmObservable = this.WhenAnyValue(x => x.SelectedPrSm).Where(prsm => prsm != null);
prsmObservable
.Select(prsm => prsm.GetFragmentationSequence()).Where(fragSeq => fragSeq != null)
.Subscribe(fragSeq =>
{
this.SpectrumViewModel.FragmentationSequence = fragSeq;
this.XicViewModel.FragmentationSequence = fragSeq;
});
// When the prsm changes, update the Scan View Model.
prsmObservable.Subscribe(prsm => this.ScanViewModel.SelectedPrSm = prsm);
// When the prsm updates, update the prsm in the sequence creator
prsmObservable.Subscribe(prsm => this.CreateSequenceViewModel.SelectedPrSm = prsm);
// When the prsm updates, update the feature map
prsmObservable.Where(_ => this.FeatureMapViewModel != null).Subscribe(prsm => this.FeatureMapViewModel.FeatureMapViewModel.SelectedPrSm = prsm);
// When prsm updates, subscribe to scan updates
prsmObservable.Subscribe(prsm =>
{
prsm.WhenAnyValue(x => x.Scan, x => x.PrecursorMz)
.Where(x => x.Item1 > 0 && x.Item2 > 0 && this.SpectrumViewModel != null)
.Subscribe(x => this.SpectrumViewModel.UpdateSpectra(x.Item1, x.Item2));
prsm.WhenAnyValue(x => x.Scan).Where(scan => scan > 0 && this.XicViewModel != null)
.Subscribe(scan => this.XicViewModel.SetSelectedScan(scan));
});
// When a new prsm is created by CreateSequenceViewModel, update SelectedPrSm
this.CreateSequenceViewModel.WhenAnyValue(x => x.SelectedPrSm).Subscribe(prsm => this.SelectedPrSm = prsm);
// When IDs are filtered in the ScanViewModel, update feature map with new IDs
this.ScanViewModel.WhenAnyValue(x => x.FilteredData).Where(_ => this.FeatureMapViewModel != null).Subscribe(data => this.FeatureMapViewModel.UpdateIds(data));
// Toggle instrument data when ShowInstrumentData setting is changed.
IcParameters.Instance.WhenAnyValue(x => x.ShowInstrumentData).Select(async x => await this.ScanViewModel.ToggleShowInstrumentDataAsync(x, (PbfLcMsRun)this.LcMs)).Subscribe();
// When product ion tolerance or ion correlation threshold change, update scorer factory
IcParameters.Instance.WhenAnyValue(x => x.ProductIonTolerancePpm, x => x.IonCorrelationThreshold)
.Subscribe(
x =>
{
var scorer = new ScorerFactory(x.Item1, Constants.MinCharge, Constants.MaxCharge, x.Item2);
this.CreateSequenceViewModel.ScorerFactory = scorer;
this.ScanViewModel.ScorerFactory = scorer;
});
// When an ID file has been opened, turn on the unidentified scan filter
this.WhenAnyValue(x => x.IdFileOpen)
.Where(idFileOpen => idFileOpen)
.Select(_ => this.ScanViewModel.Filters.FirstOrDefault(f => f.Name == "Hide Unidentified Scans"))
.Where(f => f != null)
.Subscribe(f => f.Selected = true);
// Start MsPf Search Command
var startMsPfSearchCommand = ReactiveCommand.Create();
startMsPfSearchCommand.Subscribe(_ => this.StartMsPfSearchImplementation());
this.StartMsPfSearchCommand = startMsPfSearchCommand;
// Close command verifies that the user wants to close the dataset, then sets ReadyToClose to true if they are
var closeCommand = ReactiveCommand.Create();
closeCommand.Subscribe(_ =>
{
this.ReadyToClose =
dialogService.ConfirmationBox(
string.Format("Are you sure you would like to close {0}?", this.Title), string.Empty);
});
this.CloseCommand = closeCommand;
}
