Example #1
0
        public void SolverFactoryTest()
        {
            var     model  = EmodlLoader.LoadEMODLModel(_sirModel);
            ISolver solver = SolverFactory.CreateSolver("SSA", model, 1, 2.0, 3);

            Assert.IsTrue(solver is Gillespie);
            solver = SolverFactory.CreateSolver("FIRST", model, 1, 2.0, 3);
            Assert.IsTrue(solver is GillespieFirstReaction);
            solver = SolverFactory.CreateSolver("NEXT", model, 1, 2.0, 3);
            Assert.IsTrue(solver is GibsonBruck);
            solver = SolverFactory.CreateSolver("HYBRID", model, 1, 2.0, 3);
            Assert.IsTrue(solver is HybridSSA);
            solver = SolverFactory.CreateSolver("TAU", model, 1, 2.0, 3);
            Assert.IsTrue(solver is TauLeaping);
            solver = SolverFactory.CreateSolver("MID", model, 1, 2.0, 3);
            Assert.IsTrue(solver is MidPoint);
            solver = SolverFactory.CreateSolver("R", model, 1, 2.0, 3);
            Assert.IsTrue(solver is RLeaping);
            solver = SolverFactory.CreateSolver("RFAST", model, 1, 2.0, 3);
            Assert.IsTrue(solver is RLeapingFast);
            solver = SolverFactory.CreateSolver("BLEAP", model, 1, 2.0, 3);
            Assert.IsTrue(solver is BLeaping);
            solver = SolverFactory.CreateSolver("TSSA", model, 1, 2.0, 3);
            Assert.IsTrue(solver is TransportSSA);
            solver = SolverFactory.CreateSolver("DFSP", model, 1, 2.0, 3);
            Assert.IsTrue(solver is DFSP);
            solver = SolverFactory.CreateSolver("OTSSA", model, 1, 2.0, 3);
            Assert.IsTrue(solver is OptimalTransportSSA);

/* Fractional diffusion solver doesn't handle single node models gracefully.
 *          solver = SolverFactory.CreateSolver("LEVY", model, 1, 2.0, 3);
 *          Assert.IsTrue(solver is FractionalDiffusion);
 */
/* Exit times solver doesn't handle missing target condition gracefully.
 *          solver = SolverFactory.CreateSolver("EXITTIMES", model, 1, 2.0, 3);
 *          Assert.IsTrue(solver is ExitTimes);
 */
/* dwSSA solver automatically starts solving
 *          Configuration.CurrentConfiguration = Configuration.ConfigurationFromString("{\"dwSSA\":{\"re_name\":\"I\",\"re_val\":500}}");
 *          solver = SolverFactory.CreateSolver("DWSSA", model, 1, 2.0, 3);
 *          Assert.IsTrue(solver is dwSSA);
 */
        }
Example #2
0
        public void MigrationReactions()
        {
            const string modelDescription = @"
            ; migration model

            (import (rnrs) (emodl cmslib))

            (start-model ""migration"")

            (locale site-a)
            (set-locale site-a)

            (species A::S 990)
            (species A::E)
            (species A::I 10)
            (species A::R)

            ;(observe susceptibleA A::S)
            ;(observe exposedA     A::E)
            ;(observe infectiousA  A::I)
            ;(observe recoveredA   A::R)
            (observe populationA  (sum A::S A::E A::I A::R))
            ;(observe prevalenceA (/ A::I (sum A::S A::E A::R)))

            (param Ki 0.0005)
            (param Kl 0.2)
            (param Kr (/ 1 7))
            (param Kw (/ 1 135))

            (reaction exposureA   (A::S) (A::E) (* Ki A::S A::I))
            (reaction infectionA  (A::E) (A::I) (* Kl A::E))
            (reaction recoveryA   (A::I) (A::R) (* Kr A::I))
            (reaction waningA     (A::R) (A::S) (* Kw A::R))

            (locale site-b)
            (set-locale site-b)

            (species B::S 100)
            (species B::E)
            (species B::I)
            (species B::R)

            ;(observe susceptibleB B::S)
            ;(observe exposedB     B::E)
            ;(observe infectiousB  B::I)
            ;(observe recoveredB   B::R)
            (observe populationB  (sum B::S B::E B::I B::R))
            ;(observe prevalenceB (/ B::I (sum B::S B::E B::R)))

            (reaction exposureB   (B::S) (B::E) (* Ki B::S B::I))
            (reaction infectionB  (B::E) (B::I) (* Kl B::E))
            (reaction recoveryB   (B::I) (B::R) (* Kr B::I))
            (reaction waningB     (B::R) (B::S) (* Kw B::R))

            ; migration

            (param Km 0.01)

            (reaction SA->SB (A::S) (B::S) (* Km A::S))
            (reaction EA->EB (A::E) (B::E) (* Km A::E))
            (reaction IA->IB (A::I) (B::I) (* Km A::I))
            (reaction RA->RB (A::R) (B::R) (* Km A::R))
                                
            (reaction SB->SA (B::S) (A::S) (* Km B::S 10))
            (reaction EB->EA (B::E) (A::E) (* Km B::E 10))
            (reaction IB->IA (B::I) (A::I) (* Km B::I 10))
            (reaction RB->RA (B::R) (A::R) (* Km B::R 10))

            (end-model)
            ";

            Console.WriteLine("Building model with local and migratory/diffusive reactions...");
            ModelInfo modelInfo = EmodlLoader.LoadEMODLModel(modelDescription);

            var local     = from reaction in modelInfo.Reactions where reaction.IsLocal select reaction;
            var migration = from reaction in modelInfo.Reactions where reaction.IsDiffusion select reaction;

            Console.WriteLine("Checking model for local reactions...");
            Expect(local.Count() == 8);
            Console.WriteLine("Checking model for migratory/diffusive reactions...");
            Expect(migration.Count() == 8);

            Console.WriteLine("");
        }