protected override void Context()
{
base.Context();
_compound = new Compound();
var solDim = new Dimension(new BaseDimensionRepresentation(), "Solubility", "m");
solDim.AddUnit(new Unit("cm", 0.01, 0));
_solubilityTableFormula = new TableFormula();
var solubilityTable = DomainHelperForSpecs.ConstantParameterWithValue(0).WithName(CoreConstants.Parameters.SOLUBILITY_TABLE).WithDimension(solDim);
solubilityTable.Formula = _solubilityTableFormula;
_solubilityAlternative = new ParameterAlternative {
solubilityTable
};
var solubilityAlternativeGroup = new ParameterAlternativeGroup();
solubilityAlternativeGroup.AddAlternative(_solubilityAlternative);
_compound.AddParameterAlternativeGroup(solubilityAlternativeGroup);
}
protected override void Context()
{
base.Context();
var solDim = new Dimension(new BaseDimensionRepresentation(), "Solubility", "m");
solDim.AddUnit(new Unit("cm", 0.01, 0));
_refPhValue = 7;
_solValue = 100;
_gainPerChargeValue = 1000;
A.CallTo(_formulaFactory).WithReturnType <TableFormula>().Returns(new TableFormula());
var solubilityTable = DomainHelperForSpecs.ConstantParameterWithValue(0).WithName(CoreConstants.Parameters.SOLUBILITY_TABLE).WithDimension(solDim);
var refPh = DomainHelperForSpecs.ConstantParameterWithValue(_refPhValue).WithName(CoreConstants.Parameters.REFERENCE_PH).WithDimension(DomainHelperForSpecs.NoDimension());
var solubilty = DomainHelperForSpecs.ConstantParameterWithValue(_solValue).WithName(CoreConstants.Parameters.SOLUBILITY_AT_REFERENCE_PH).WithDimension(solDim);
var gainPerCharge = DomainHelperForSpecs.ConstantParameterWithValue(_gainPerChargeValue).WithName(CoreConstants.Parameters.SOLUBILITY_GAIN_PER_CHARGE).WithDimension(DomainHelperForSpecs.NoDimension());
_solubility_pKa_pH_Factor = new PKSimParameter().WithName(CoreConstants.Parameters.SOLUBILITY_P_KA__P_H_FACTOR);
_solubility_pKa_pH_Factor.Formula = new ExplicitFormula("10 * (pH +1)");
_solubility_pKa_pH_Factor.Formula.AddObjectPath(new FormulaUsablePath(new[] { ObjectPath.PARENT_CONTAINER, CoreConstants.Parameters.REFERENCE_PH }).WithAlias("pH"));
_compoundForCalculation = new Compound {
refPh, solubilty, gainPerCharge, _solubility_pKa_pH_Factor
};
_solubilityAlternative = new ParameterAlternative {
refPh, solubilty, gainPerCharge, solubilityTable
};
var solubilityAlternativeGroup = new ParameterAlternativeGroup();
solubilityAlternativeGroup.AddAlternative(_solubilityAlternative);
_originalRefPh = DomainHelperForSpecs.ConstantParameterWithValue(_refPhValue).WithName(CoreConstants.Parameters.REFERENCE_PH).WithDimension(DomainHelperForSpecs.NoDimension());
_originalRefPh.Value = 4;
_compound = new Compound {
_originalRefPh
};
_compound.AddParameterAlternativeGroup(solubilityAlternativeGroup);
A.CallTo(() => _executionContext.Clone(_compound)).Returns(_compoundForCalculation);
}
