Ejemplo n.º 1
0
            public SrmDocument ChangePeak(SrmDocument doc, SrmTreeNode nodePepTree, TransitionGroupDocNode nodeTranGroup, string nameSet, MsDataFileUri filePath)
            {
                if ((_retentionTime ?? StartTime) == null)
                {
                    return(doc);
                }

                var groupPath = new IdentityPath(nodePepTree.Path, nodeTranGroup.Id);

                doc = _retentionTime.HasValue
                    ? doc.ChangePeak(groupPath, nameSet, filePath, null, _retentionTime.Value, UserSet.TRUE)
                    : doc.ChangePeak(groupPath, nameSet, filePath, null, StartTime, EndTime, UserSet.TRUE, null, false);

                var activeTransitionGroup = (TransitionGroupDocNode)doc.FindNode(groupPath);

                if (activeTransitionGroup.RelativeRT != RelativeRT.Matching)
                {
                    return(doc);
                }

                var activeChromInfo = SkylineWindow.FindChromInfo(doc, activeTransitionGroup, nameSet, filePath);
                var peptide         = (PeptideDocNode)doc.FindNode(groupPath.Parent);

                // See if there are any other transition groups that should have their peak bounds set to the same value
                foreach (var tranGroup in peptide.TransitionGroups.Where(tranGroup => tranGroup.RelativeRT == RelativeRT.Matching))
                {
                    var otherGroupPath = new IdentityPath(groupPath.Parent, tranGroup.TransitionGroup);
                    if (Equals(groupPath, otherGroupPath) || SkylineWindow.FindChromInfo(doc, tranGroup, nameSet, filePath) == null)
                    {
                        continue;
                    }

                    doc = doc.ChangePeak(otherGroupPath, nameSet, filePath, null,
                                         activeChromInfo.StartRetentionTime, activeChromInfo.EndRetentionTime, UserSet.TRUE, activeChromInfo.Identified, false);
                }
                return(doc);
            }