private AscvdParameters(Patient patient,
BloodPressure bloodPressure,
QuantitativeLab totalCholesterol,
QuantitativeLab ldlCholesterol,
QuantitativeLab hdlCholesterol)
{
Patient = patient ?? throw new ArgumentNullException(nameof(patient));
BloodPressure = bloodPressure ?? throw new ArgumentNullException(nameof(bloodPressure));
TotalCholesterol = totalCholesterol ?? throw new ArgumentNullException(nameof(totalCholesterol));
LdlCholesterol = ldlCholesterol ?? throw new ArgumentNullException(nameof(ldlCholesterol));
HdlCholesterol = hdlCholesterol ?? throw new ArgumentNullException(nameof(hdlCholesterol));
if (totalCholesterol.Type != QuantitativeLabType.CholesterolTotalSerum)
{
throw new InvalidEnumArgumentException(
$"{nameof(totalCholesterol.Type)}. Should be {nameof(QuantitativeLabType.CholesterolTotalSerum)}");
}
if (ldlCholesterol.Type != QuantitativeLabType.LowDensityLipoproteinSerum)
{
throw new InvalidEnumArgumentException(
$"{nameof(ldlCholesterol.Type)}. Should be {nameof(QuantitativeLabType.LowDensityLipoproteinSerum)}");
}
if (hdlCholesterol.Type != QuantitativeLabType.HighDensityLipoproteinSerum)
{
throw new InvalidEnumArgumentException(
$"{nameof(hdlCholesterol.Type)}. Should be {nameof(QuantitativeLabType.HighDensityLipoproteinSerum)}");
}
}
public void Build_GivenNullTotalCholesterol_ThrowsArgumentNullException()
{
_totalCholesterol = null;
Assert.Throws <ArgumentNullException>(
() => AscvdParameters.Build(_patient, _bloodPressure, _totalCholesterol, _ldlCholesterol,
_hdlCholesterol));
}
public PooledCohortsEquation(PooledCohortEquationParameters parameters)
{
if (parameters == null)
{
throw new ArgumentNullException(nameof(parameters));
}
_hdlCholesterol = parameters.HdlCholesterol ??
throw new ArgumentNullException(nameof(parameters.HdlCholesterol));
_totalCholesterol = parameters.TotalCholesterol ??
throw new ArgumentNullException(nameof(parameters.TotalCholesterol));
_bloodPressure = parameters.BloodPressure ??
throw new ArgumentNullException(nameof(parameters.BloodPressure));
_patient = parameters.Patient ?? throw new ArgumentNullException(nameof(parameters.Patient));
_hypertensionTreatment = parameters.HypertensionTreatment;
_smoker = parameters.Smoker;
_diabetic = parameters.Diabetic;
if (parameters.TotalCholesterol.Type != QuantitativeLabType.CholesterolTotalSerum)
{
throw new InvalidEnumArgumentException(
$"{nameof(parameters.TotalCholesterol)} should have an enum 'Type' of {nameof(QuantitativeLabType.CholesterolTotalSerum)}.");
}
if (parameters.HdlCholesterol.Type != QuantitativeLabType.HighDensityLipoproteinSerum)
{
throw new InvalidEnumArgumentException(
$"{nameof(parameters.HdlCholesterol)} should have an enum 'Type' of {nameof(QuantitativeLabType.HighDensityLipoproteinSerum)}.");
}
}
internal PooledCohortEquationParameters()
{
Patient = new Patient();
BloodPressure = new BloodPressure();
TotalCholesterol = new QuantitativeLab();
HdlCholesterol = new QuantitativeLab();
}
public static AscvdParameters Build(Patient patient,
BloodPressure bloodPressure,
QuantitativeLab totalCholesterol,
QuantitativeLab ldlCholesterol,
QuantitativeLab hdlCholesterol)
{
return(new AscvdParameters(patient, bloodPressure, totalCholesterol, ldlCholesterol, hdlCholesterol));
}
public CompleteBloodCountWithDifferential()
{
Neutrophils = new QuantitativeLab();
Lymphocytes = new QuantitativeLab();
Basophils = new QuantitativeLab();
Eosinophils = new QuantitativeLab();
Monocytes = new QuantitativeLab();
}
internal static PooledCohortEquationParameters Build(
Patient patient,
BloodPressure bloodPressure,
QuantitativeLab totalCholesterol,
QuantitativeLab hdlCholesterol)
{
return(new PooledCohortEquationParameters(patient, bloodPressure, totalCholesterol, hdlCholesterol));
}
public QuantitativeLabClassification(
QuantitativeLabClassificationParameters quantitativeLabClassificationParameters)
{
_lab = quantitativeLabClassificationParameters.Lab ??
throw new ArgumentNullException(nameof(quantitativeLabClassificationParameters.Lab));
_patient = quantitativeLabClassificationParameters.Patient ??
throw new ArgumentNullException(nameof(quantitativeLabClassificationParameters.Patient));
Lab = QuantitativeLabRepository.GetLab(quantitativeLabClassificationParameters.Lab);
}
public ComprehensiveMetabolicPanel()
{
TotalProtein = new QuantitativeLab();
Albumin = new QuantitativeLab();
AlkalinePhosphatase = new QuantitativeLab();
TotalBilirubin = new QuantitativeLab();
AlanineAminotransferase = new QuantitativeLab();
AspartateAminotransferase = new QuantitativeLab();
}
public BasicMetabolicPanel()
{
Sodium = new QuantitativeLab();
Potassium = new QuantitativeLab();
Chloride = new QuantitativeLab();
Bicarbonate = new QuantitativeLab();
BloodUreaNitrogen = new QuantitativeLab();
Creatinine = new QuantitativeLab();
Glucose = new QuantitativeLab();
}
private void CheckForNullParameters(AscvdParameters ascvdParameters)
{
_cholesterolHdlC = ascvdParameters.HdlCholesterol ??
throw new ArgumentNullException(nameof(ascvdParameters.HdlCholesterol));
_cholesterolTotal = ascvdParameters.TotalCholesterol ??
throw new ArgumentNullException(nameof(ascvdParameters.TotalCholesterol));
_ldlCholesterol = ascvdParameters.LdlCholesterol ??
throw new ArgumentNullException(nameof(ascvdParameters.LdlCholesterol));
_bloodPressure = ascvdParameters.BloodPressure ??
throw new ArgumentNullException(nameof(ascvdParameters.BloodPressure));
_patient = ascvdParameters.Patient ?? throw new ArgumentNullException(nameof(ascvdParameters.Patient));
}
public CompleteBloodCount()
{
WhiteBloodCells = new QuantitativeLab();
RedBloodCells = new QuantitativeLab();
MeanCorpuscularVolume = new QuantitativeLab();
MeanCorpuscularHemoglobin = new QuantitativeLab();
MeanCorpuscularHemoglobinConcentration = new QuantitativeLab();
RedCellDistributionWidth = new QuantitativeLab();
Hemoglobin = new QuantitativeLab();
Hematocrit = new QuantitativeLab();
Platelets = new QuantitativeLab();
}
private PooledCohortEquationParameters(
Patient patient,
BloodPressure bloodPressure,
QuantitativeLab totalCholesterol,
QuantitativeLab hdlCholesterol) : this()
{
Patient = patient ?? throw new ArgumentNullException(nameof(patient));
BloodPressure = bloodPressure ?? throw new ArgumentNullException(nameof(bloodPressure));
TotalCholesterol = totalCholesterol ?? throw new ArgumentNullException(nameof(totalCholesterol));
HdlCholesterol = hdlCholesterol ?? throw new ArgumentNullException(nameof(hdlCholesterol));
HypertensionTreatment = patient.Comorbidities.Contains(ChronicDisease.HypertensionTreated);
Smoker = patient.Comorbidities.Contains(ChronicDisease.TobaccoSmoker);
Diabetic = patient.Comorbidities.Contains(ChronicDisease.Diabetes);
}
public AscvdParameters()
{
Patient = new Patient();
BloodPressure = new BloodPressure();
TotalCholesterol = new QuantitativeLab {
Type = QuantitativeLabType.CholesterolTotalSerum
};
HdlCholesterol = new QuantitativeLab {
Type = QuantitativeLabType.HighDensityLipoproteinSerum
};
LdlCholesterol = new QuantitativeLab {
Type = QuantitativeLabType.LowDensityLipoproteinSerum
};
}
public static QuantitativeLab WhiteBloodCells(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.WhiteBloodCellsUrine));
}
public static QuantitativeLab Glucose(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.GlucoseSerum));
}
public static QuantitativeLab Hemoglobin(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.HemoglobinUrine));
}
public static QuantitativeLab Ketones(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.KetonesUrine));
}
public static QuantitativeLabClassificationModel GetLab(QuantitativeLab lab)
{
return(GetAllLabs().First(l =>
string.Equals(l.LabName.ToString(), lab.Type.ToString(), StringComparison.CurrentCultureIgnoreCase)));
}
public static QuantitativeLab LowDensityLipoprotein(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.LowDensityLipoproteinSerum));
}
public static QuantitativeLab AlanineTransaminase(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.AlanineTransaminaseSerum));
}
public static QuantitativeLab LdlParticleSizeMean(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.LdlParticleSizeMeanSerum));
}
public static QuantitativeLab CholesterolTotal(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.CholesterolTotalSerum));
}
public static QuantitativeLab Sodium(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.SodiumSerum));
}
public static QuantitativeLab CReactiveProtein(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.CReactiveProteinSerum));
}
public static QuantitativeLab Albumin(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.AlbuminSerum));
}
public static QuantitativeLab Protein(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.ProteinUrine));
}
public QuantitativeLabClassificationParameters(QuantitativeLab lab, Patient patient)
{
Lab = lab;
Patient = patient;
}
public static QuantitativeLab BilirubinTotal(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.BilirubinTotalSerum));
}
public static QuantitativeLab AlkalinePhosphatase(double result)
{
return(QuantitativeLab.Create(result, QuantitativeLabType.AlkalinePhosphataseSerum));
}
