protected override void Context()
{
base.Context();
_para1 = new Parameter().WithName("Para1");
_para2 = new Parameter().WithName("Para2");
_moleculeBuilder = new MoleculeBuilder().WithName("tralal");
_moleculeBuilder.IsFloating = true;
_moleculeBuilder.IsXenobiotic = true;
_moleculeBuilder.Add(_para1);
_moleculeBuilder.Add(_para2);
_moleculeContainer = A.Fake <IContainer>();
A.CallTo(() => _containerTask.CreateOrRetrieveSubContainerByName(_rootContainer, _moleculeBuilder.Name)).Returns(_moleculeContainer);
_globalMoleculeDependentProperties = new Container();
A.CallTo(() => _parameterCollectionMapper.MapGlobalOrPropertyFrom(_moleculeBuilder, _buildConfiguration))
.Returns(new[] { _para1, _para2 });
_globalMoleculeDepParam1 = new Parameter().WithName("GMDP1");
_globalMoleculeDepParam2 = new Parameter().WithName("GMDP2");
_globalMoleculeDependentProperties.Add(_globalMoleculeDepParam1);
_globalMoleculeDependentProperties.Add(_globalMoleculeDepParam2);
A.CallTo(() => _parameterCollectionMapper.MapAllFrom(_globalMoleculeDependentProperties, _buildConfiguration))
.Returns(new[] { _globalMoleculeDepParam1, _globalMoleculeDepParam2 });
_buildConfiguration.SpatialStructure = A.Fake <ISpatialStructure>();
A.CallTo(() => _buildConfiguration.SpatialStructure.GlobalMoleculeDependentProperties).Returns(_globalMoleculeDependentProperties);
}
protected override void Context()
{
_containerTask = A.Fake <IContainerTask>();
_objectBaseFactory = A.Fake <IObjectBaseFactory>();
_projectRetriever = A.Fake <IMoBiProjectRetriever>();
_eventPublisher = A.Fake <IEventPublisher>();
_cloneManagerForModel = A.Fake <ICloneManagerForModel>();
_formulaTask = A.Fake <IFormulaTask>();
sut = new PassiveTransportConverter(_objectBaseFactory, _projectRetriever, _containerTask, _eventPublisher, _cloneManagerForModel, _formulaTask);
A.CallTo(() => _containerTask.CreateUniqueName(A <IEnumerable <IWithName> > ._, A <string> ._, true))
.ReturnsLazily(x => x.Arguments[1].ToString());
_passiveTransportKinetic = new ExplicitFormula("1+2");
_moleculeWithPassiveTransport = new MoleculeBuilder().WithName("MOLECULE");
_passiveTransport = new TransportBuilder().WithName("PASSIVE TRANSPORT").WithFormula(_passiveTransportKinetic);
_moleculeWithPassiveTransport.Add(_passiveTransport);
_passiveTransports = new PassiveTransportBuildingBlock();
_molecules = new MoleculeBuildingBlock {
_moleculeWithPassiveTransport
}.WithName("MBB");
_project = new MoBiProject();
A.CallTo(() => _projectRetriever.Current).Returns(_project);
A.CallTo(() => _eventPublisher.PublishEvent(A <ShowNotificationsEvent> ._))
.Invokes(x => _showNotificationEvent = x.GetArgument <ShowNotificationsEvent>(0));
}
private void addCalculatedSpecificIntestinalPermeabilityTranscellularParameterTo(IMoleculeBuilder moleculeBuilder, IFormula formula, IDimension dimension)
{
if (!isPKSimMolecule(moleculeBuilder))
{
return;
}
moleculeBuilder.Add(_objectBaseFactory
.Create <IParameter>()
.WithName("Calculated specific intestinal permeability (transcellular)")
.WithFormula(formula)
.WithDimension(dimension)
.WithMode(ParameterBuildMode.Global));
}
private void addDrugParametersTo(IMoleculeBuilder molecule, IFormulaCache formulaCache)
{
var allExistingParameters = molecule.AllParameters().ToList();
molecule.Name = CoreConstants.Molecule.Drug;
_parameterContainerTask.AddMoleculeParametersTo(molecule, formulaCache);
foreach (var parameter in molecule.AllParameters().Where(p => !allExistingParameters.Contains(p)))
{
parameter.BuildingBlockType = PKSimBuildingBlockType.Simulation;
parameter.Visible = false;
parameter.CanBeVariedInPopulation = false;
molecule.Add(parameter);
}
setDefaultParameterValues(molecule);
//default value for floating in lumen should be 0
molecule.Parameter(CoreConstants.Parameter.IS_FLOATING_IN_LUMEN).Value = 0;
}