protected override void Context()
{
base.Context();
var ontogeny1 = new DatabaseOntogeny {
SpeciesName = "Dog", Name = "CYP3A1"
};
var ontogeny2 = new DatabaseOntogeny {
SpeciesName = "Dog", Name = "CYP3A2"
};
var ontogeny3 = new DatabaseOntogeny {
SpeciesName = "Dog", Name = "CYP3A3"
};
_originData = new OriginData {
Species = new Species {
Name = "Dog"
}
};
A.CallTo(() => _ontogenyRepository.AllFor(_originData.Species.Name)).Returns(new[] { ontogeny1, ontogeny2, ontogeny3 });
A.CallTo(() => _ontogenyRepository.OntogenyFactorFor(ontogeny1, CoreConstants.Groups.ONTOGENY_LIVER, _originData, null)).Returns(0.1);
A.CallTo(() => _ontogenyRepository.OntogenyFactorFor(ontogeny2, CoreConstants.Groups.ONTOGENY_DUODENUM, _originData, null)).Returns(0.22);
A.CallTo(() => _ontogenyRepository.OntogenyFactorFor(ontogeny2, CoreConstants.Groups.ONTOGENY_LIVER, _originData, null)).Returns(0.21);
A.CallTo(() => _ontogenyRepository.OntogenyFactorFor(ontogeny3, CoreConstants.Groups.ONTOGENY_LIVER, _originData, null)).Returns(0.31);
_moleculeNames.Add(new MoleculeOntogeny("CYP1", "CYP3A1"));
_moleculeNames.Add(new MoleculeOntogeny("CYP2", "CYP3A2"));
_moleculeNames.Add(new MoleculeOntogeny("CYP3", "CYP3A3"));
_moleculeNames.Add(new MoleculeOntogeny("CYP4", "ENZYME_NOT_FOUND"));
}
protected override async Task Context()
{
await base.Context();
_ontogeny = new DatabaseOntogeny
{
Name = "Database",
Description = "Database description"
};
}
public void should_retrieve_new_agp_ontogeny()
{
var ontogenyRepo = IoC.Resolve <IOntogenyRepository>();
var ontogeny = new DatabaseOntogeny {
Name = CoreConstants.Molecule.AGP, SpeciesName = CoreConstants.Species.HUMAN
};
var agpOntogenies = ontogenyRepo.AllValuesFor(ontogeny).OrderBy(onto => onto.PostmenstrualAge).ToArray();
agpOntogenies.Length.ShouldBeEqualTo(19);
agpOntogenies[0].PostmenstrualAge.ShouldBeEqualTo(0.76, 1e-2);
agpOntogenies[agpOntogenies.Length - 1].PostmenstrualAge.ShouldBeEqualTo(90.45, 1e-2);
foreach (var agpOntogeny in agpOntogenies)
{
agpOntogeny.Deviation.ShouldBeGreaterThan(1.44);
agpOntogeny.Deviation.ShouldBeSmallerThan(1.89);
}
}