private void range_clk(object sender, RoutedEventArgs e)
{
PlotModel model = null;
if (mainW.display_tab.SelectedIndex == 0) //显示的是MS1
{
model = mainW.Model1;
}
else if (mainW.display_tab.SelectedIndex == 1) //显示的是MS2
{
model = mainW.Model2;
}
double min_mz = model.Axes[1].AbsoluteMinimum;
double max_mz = model.Axes[1].AbsoluteMaximum;
if (Config_Help.IsDecimalAllowed(this.minMZ_txt.Text))
{
min_mz = double.Parse(this.minMZ_txt.Text);
}
if (Config_Help.IsDecimalAllowed(this.maxMZ_txt.Text))
{
max_mz = double.Parse(this.maxMZ_txt.Text);
}
mainW.zoom(min_mz, max_mz, model);
}
private void filter_btn_clk(object sender, RoutedEventArgs e)
{
string ac = protein_filter_AC_tb.Text;
string de = protein_filter_DE_tb.Text;
string group = protein_filter_Group_tb.Text;
int pep_number = 0, sq_number = 0;
int target_index = this.target_comboBox.SelectedIndex;
bool is_con = (bool)this.con_need_cbx.IsChecked;
if (protein_peptide_number_tb.Text == "")
{
pep_number = 0;
}
else
{
if (!Config_Help.IsIntegerAllowed(protein_peptide_number_tb.Text))
{
MessageBox.Show(Message_Help.PROTEIN_PEP_NUMBER);
return;
}
else
{
pep_number = int.Parse(protein_peptide_number_tb.Text);
}
}
if (protein_sq_number_tb.Text == "")
{
sq_number = 0;
}
else
{
if (!Config_Help.IsIntegerAllowed(protein_sq_number_tb.Text))
{
MessageBox.Show(Message_Help.PROTEIN_PEP_NUMBER);
return;
}
else
{
sq_number = int.Parse(protein_sq_number_tb.Text);
}
}
ObservableCollection <Protein> proteins = mainW.protein_panel.identification_proteins;
proteins = filter_by_AC(ac, proteins);
proteins = filter_by_DE(de, proteins);
proteins = filter_by_Group(group, proteins);
proteins = filter_by_Pep_number(pep_number, proteins);
proteins = filter_by_Sq_number(sq_number, proteins);
proteins = filter_byTarget(target_index, proteins);
proteins = filter_byContaminant(is_con, proteins);
mainW.protein_data.ItemsSource = proteins;
mainW.display_size.Text = proteins.Count.ToString();
this.Close();
}
public ObservableCollection <PSM> filter_bySQ_or_Title(string str, int flag, ObservableCollection <PSM> all_psms, int regular_flag = 0) //regular_flag为0表示Normal搜索，为1表示正则表达式搜索
{
if (str == "")
{
return(all_psms);
}
ObservableCollection <PSM> psms = new ObservableCollection <PSM>();
if (flag == 0)
{
if (regular_flag == 0)
{
for (int i = 0; i < all_psms.Count; ++i)
{
if (all_psms[i].Title.Contains(str))
{
psms.Add(all_psms[i]);
}
}
}
else if (regular_flag == 1)
{
for (int i = 0; i < all_psms.Count; ++i)
{
if (Config_Help.IsMatch_RegularExpression(all_psms[i].Title, str))
{
psms.Add(all_psms[i]);
}
}
}
}
else if (flag == 1)
{
if (regular_flag == 0)
{
for (int i = 0; i < all_psms.Count; ++i)
{
if (all_psms[i].Sq.Contains(str))
{
psms.Add(all_psms[i]);
}
}
}
else if (regular_flag == 1)
{
for (int i = 0; i < all_psms.Count; ++i)
{
if (Config_Help.IsMatch_RegularExpression(all_psms[i].Sq, str))
{
psms.Add(all_psms[i]);
}
}
}
}
return(psms);
}
private void add_btn_clk(object sender, RoutedEventArgs e)
{
string name = name_tb.Text;
if (!Config_Help.IsDecimalAllowed(mass_tb.Text))
{
return;
}
double mass = double.Parse(mass_tb.Text);
Denovol_Config.All_mass.Add(new Denovol_Config.DCC(mass, name));
update();
}
private void update_element()
{
if (this.Mod == "")
{
this.Element = "";
this.Mass = "";
return;
}
int index = Config_Help.get_label_index(this.Mod_Flag);
Aa[] aas = Config_Help.modStr_elements_hash[this.Mod] as Aa[];
double[] masses = Config_Help.modStr_hash[this.Mod] as double[];
if (aas == null || aas[index] == null || masses == null || masses[index] == null)
{
return;
}
this.Element = pBuild.Aa.parse_String_byAa(aas[index]);
this.Mass = masses[index].ToString("F2");
}
private void ok_btn_clk(object sender, RoutedEventArgs e)
{
List <double> masses = new List <double>();
List <double> mass_errors = new List <double>();
List <int> mass_error_flags = new List <int>();
bool flag = true;
for (int i = 0; i < this.grid.RowDefinitions.Count; ++i)
{
TextBox tbx1 = this.grid.Children[i * 4 + 1] as TextBox;
TextBox tbx2 = this.grid.Children[i * 4 + 2] as TextBox;
ComboBox cb = this.grid.Children[i * 4 + 3] as ComboBox;
string cb_str = cb.SelectedItem as string;
if (!Config_Help.IsDecimalAllowed(tbx1.Text) || !Config_Help.IsDecimalAllowed(tbx2.Text))
{
flag = false;
break;
}
masses.Add(double.Parse(tbx1.Text));
double mass_error = double.Parse(tbx2.Text);
int me_flag = 1;
if (cb_str == "ppm")
{
mass_error = mass_error * 1e-6;
me_flag = 0;
}
mass_errors.Add(mass_error);
mass_error_flags.Add(me_flag);
}
if (!flag)
{
MessageBox.Show(Message_Help.ALL_TERM_BE_DOUBLE);
return;
}
this.mainW.ms2_quant_help2 = new MS2_Quant_Help2(masses, mass_errors, mass_error_flags);
this.Cursor = Cursors.Wait;
this.mainW.ms2_quant2();
this.Close();
this.Cursor = null;
}
private void ok_btn(object sender, RoutedEventArgs e)
{
string n1_str = this.n_term1_tbx.Text;
string n2_str = this.n_term2_tbx.Text;
string c1_str = this.c_term1_tbx.Text;
string c2_str = this.c_term2_tbx.Text;
string me_str = this.mass_error_tbx.Text;
string n1_aa_str = this.n_term1_aa_tbx.Text;
string n2_aa_str = this.n_term2_aa_tbx.Text;
string c1_aa_str = this.c_term1_aa_tbx.Text;
string c2_aa_str = this.c_term2_aa_tbx.Text;
string mz1_str = this.mz1_tbx.Text;
string mz2_str = this.mz2_tbx.Text;
Config_Help.MS2_Match_Ion_Type = this.match_Ion_type_tbx.Text;
if (!Config_Help.IsDecimalAllowed(n1_str) || !Config_Help.IsDecimalAllowed(n2_str) || !Config_Help.IsDecimalAllowed(c1_str) ||
!Config_Help.IsDecimalAllowed(c2_str) || !Config_Help.IsDecimalAllowed(me_str))
{
MessageBox.Show(Message_Help.ALL_TERM_BE_DOUBLE);
return;
}
if (!Config_Help.IsRightAA(n1_aa_str) || !Config_Help.IsRightAA(n2_aa_str) || !Config_Help.IsRightAA(c1_aa_str) ||
!Config_Help.IsRightAA(c2_aa_str))
{
MessageBox.Show(Message_Help.ALL_AA_WRONG);
return;
}
if (!Config_Help.IsDecimalAllowed(mz1_str) || !Config_Help.IsDecimalAllowed(mz2_str))
{
MessageBox.Show(Message_Help.ALL_TERM_BE_DOUBLE);
return;
}
double n1_mass = double.Parse(n1_str);
double n2_mass = double.Parse(n2_str);
double c1_mass = double.Parse(c1_str);
double c2_mass = double.Parse(c2_str);
double me_mass = double.Parse(me_str);
double mz1 = double.Parse(mz1_str);
double mz2 = double.Parse(mz2_str);
if (this.mass_error_cb.SelectedIndex == 0)
{
mainW.ms2_quant_help = new MS2_Quant_Help(n1_mass, n2_mass, c1_mass, c2_mass, n1_aa_str,
n2_aa_str, c1_aa_str, c2_aa_str, me_mass * 1e-6, 0.0, mz1, mz2);
}
else
{
mainW.ms2_quant_help = new MS2_Quant_Help(n1_mass, n2_mass, c1_mass, c2_mass, n1_aa_str,
n2_aa_str, c1_aa_str, c2_aa_str, 0.0, me_mass, mz1, mz2);
}
this.Cursor = Cursors.Wait;
mainW.ms2_quant();
this.Close();
this.Cursor = null;
}
private void filter_btn(object sender, RoutedEventArgs e)
{
try
{
string title_str = this.title_subStr_txt.Text;
int title_regular_flag = this.title_cbb.SelectedIndex;
string sq_str = this.sq_subStr_txt.Text;
int sq_regular_flag = this.sq_cbb.SelectedIndex;
ComboBoxItem selected_item = (ComboBoxItem)this.mods_comboBox.SelectedItem;
ComboBoxItem selected_item_flag = (ComboBoxItem)this.mods_comboBox2.SelectedItem;
string mod_name = selected_item.Content.ToString();
string mod_name1 = mod_name;
string mod_flag = selected_item_flag.Content.ToString();
if (mod_name == "Show All")
{
mod_name = "";
}
if (mod_flag != "Show All")
{
int index = 0;
for (int i = 0; i < Config_Help.mod_label_name.Count(); ++i)
{
if (Config_Help.mod_label_name[i] == mod_flag)
{
index = i;
break;
}
}
mod_name = mod_name + "#" + index;
}
ComboBoxItem selected_item2 = (ComboBoxItem)this.specific_comboBox.SelectedItem;
string specific_name = selected_item2.Content.ToString();
if (this.filter_mix_num.Text != "" && !Config_Help.IsIntegerAllowed(this.filter_mix_num.Text))
{
MessageBox.Show(Message_Help.MIXED_NUMBER_BE_INTEGER);
return;
}
int mix_num = 0;
if (this.filter_mix_num.Text != "")
{
mix_num = int.Parse(this.filter_mix_num.Text);
}
if (this.ratio_tbx.Text != "" && !Config_Help.IsDecimalAllowed(this.ratio_tbx.Text) &&
this.ratio_tbx2.Text != "" && !Config_Help.IsDecimalAllowed(this.ratio_tbx2.Text))
{
MessageBox.Show(Message_Help.RATIO_NUMBER_BE_DOUBLE);
return;
}
ComboBoxItem selected_item3 = (ComboBoxItem)this.label_comboBox.SelectedItem;
string label_name = selected_item3.Content.ToString();
string label_name1 = label_name;
if (label_name == "Show All")
{
label_name = "";
}
double ratio = 1024.0;
double ratio2 = 0.0;
double sigma = 1.0;
double sigma2 = 0.0;
if (this.ratio_tbx.Text != "")
{
ratio = double.Parse(this.ratio_tbx.Text);
}
if (this.ratio_tbx2.Text != "")
{
ratio2 = double.Parse(this.ratio_tbx2.Text);
}
if (this.sigma_tbx.Text != "")
{
sigma = double.Parse(this.sigma_tbx.Text);
}
if (this.sigma_tbx2.Text != "")
{
sigma2 = double.Parse(this.sigma_tbx2.Text);
}
ObservableCollection <PSM> display_psms = new ObservableCollection <PSM>();
ObservableCollection <PSM> all_psms = new ObservableCollection <PSM>();
if (!(bool)mainW.other_psms_cbx.IsChecked)
{
all_psms = mainW.psms;
}
else
{
for (int i = 0; i < mainW.all_psms.Count; ++i)
{
if (mainW.all_psms[i].Q_value > Config_Help.fdr_value)
{
all_psms.Add(mainW.all_psms[i]);
}
}
}
ComboBoxItem selected_item_target = (ComboBoxItem)this.target_comboBox.SelectedItem;
string target_string = selected_item_target.Content.ToString();
int target_index = 0;
if (target_string == "Show All")
{
target_index = 0;
}
else if (target_string == "Target")
{
target_index = 1;
}
else if (target_string == "Decoy")
{
target_index = 2;
}
display_psms = filter_byTarget(target_index, all_psms);
display_psms = filter_bySQ_or_Title(title_str, 0, display_psms, title_regular_flag);
display_psms = filter_bySQ_or_Title(sq_str, 1, display_psms, sq_regular_flag);
display_psms = filter_byMod(mod_name, display_psms);
display_psms = filter_bySpecific(specific_name, display_psms);
display_psms = filter_byLabelName(label_name, display_psms);
display_psms = filter_byRatio_Less(ratio, display_psms);
display_psms = filter_byRatio_Bigger(ratio2, display_psms);
display_psms = filter_bySigma_Less(sigma, display_psms);
display_psms = filter_bySigma_Bigger(sigma2, display_psms);
display_psms = filter_byContaminant((bool)this.con_need_cbx.IsChecked, display_psms);
display_psms = filter_byUnqiue((bool)this.unique_cbx.IsChecked, display_psms);
display_psms = filter_byMix_Bigger(mix_num, display_psms);
mainW.display_psms = display_psms;
mainW.data.ItemsSource = display_psms;
mainW.display_size.Text = display_psms.Count.ToString();
Config_Help.psm_filter_bean = new PSM_Filter_Bean(mix_num, title_str, title_regular_flag, sq_str, sq_regular_flag, mod_name1, mod_flag, specific_name, label_name1, target_string,
(bool)this.con_need_cbx.IsChecked, (bool)this.unique_cbx.IsChecked, ratio, ratio2, sigma, sigma2);
//this.Close();
}
catch (Exception exe)
{
MessageBox.Show(exe.ToString());
}
}