private void CreateInitialGraph(DGraph dgraph)
{
var nodeA0 = dgraph.AddNode("A0");
dgraph.AddNode("A1");
dgraph.AddNode("A2");
var nodeA3 = dgraph.AddNode("A3");
nodeA0.Node.Attr.Shape = Microsoft.Msagl.Drawing.Shape.Box;
nodeA0.Node.Attr.XRadius = 5.0;
nodeA0.Node.Attr.YRadius = 5.0;
var edgeA0A1 = dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A0"], dgraph.NodeMap["A1"]);
dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A0"], dgraph.NodeMap["A2"]);
dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A2"], dgraph.NodeMap["A1"]);
dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A0"], dgraph.NodeMap["A3"]);
nodeA0.Label = new DTextLabel(nodeA0, new Microsoft.Msagl.Drawing.Label()) { Text = "Node A0" };
nodeA3.Label = new DTextLabel(nodeA3, new Microsoft.Msagl.Drawing.Label()) { Text = "Node A3" };
edgeA0A1.Label = new DTextLabel(edgeA0A1, new Microsoft.Msagl.Drawing.Label()) { Text = "Edge A0->A1" };
}
private void CreateInitialGraph(DGraph dgraph)
{
var nodeA0 = dgraph.AddNode("A0");
nodeA0.Node.Attr.Shape = Microsoft.Msagl.Drawing.Shape.Box;
nodeA0.Node.Attr.XRadius = 5.0;
nodeA0.Node.Attr.YRadius = 5.0;
nodeA0.Node.Attr.FillColor = Microsoft.Msagl.Drawing.Color.Green;
nodeA0.Label = new DTextLabel(nodeA0, new Microsoft.Msagl.Drawing.Label()) { Text = "Node A0", Margin = new Thickness(5.0, 2.0, 5.0, 2.0) };
dgraph.AddNode("A1");
dgraph.AddNode("A2").Node.Attr.FillColor = Microsoft.Msagl.Drawing.Color.Blue;
var nodeA3 = dgraph.AddNode("A3");
var edgeA0A1 = dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A0"], dgraph.NodeMap["A1"]);
dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A0"], dgraph.NodeMap["A2"]);
dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A2"], dgraph.NodeMap["A1"]);
dgraph.AddEdgeBetweenNodes(dgraph.NodeMap["A0"], dgraph.NodeMap["A3"]);
nodeA3.Label = new DTextLabel(nodeA3, new Microsoft.Msagl.Drawing.Label()) { Text = "Node A3" };
edgeA0A1.Label = new DTextLabel(edgeA0A1, new Microsoft.Msagl.Drawing.Label()) { Text = "Edge A0->A1" };
dgraph.Graph.Attr.LayerDirection = Microsoft.Msagl.Drawing.LayerDirection.RL;
}
private void CreateNestedGraph()
{
var g = GraphControlForNesting.Graph;
// Create first nested graph.
var inner1 = new DGraph() { Name = "Inner 1" };
var node11 = inner1.AddNode("ID1.1");
var node12 = inner1.AddNode("ID1.2");
var edge11_12 = inner1.AddEdgeBetweenNodes(node11, node12);
// Create second nested graph.
var inner3 = new DGraph() { Name = "Inner 2" };
var node31 = inner3.AddNode("ID3.1");
var node32 = inner3.AddNode("ID3.2");
var edge31_32 = inner3.AddEdgeBetweenNodes(node31, node32);
// Create outer graph.
var node1 = g.AddNode("ID1");
node1.Label = new DNestedGraphLabel(node1, inner1);
node1.DrawingNode.Attr.Shape = Microsoft.Msagl.Drawing.Shape.Box;
var node2 = g.AddNode("ID2");
var node3 = g.AddNode("ID3");
node3.Label = new DNestedGraphLabel(node3, inner3);
node3.DrawingNode.Attr.Shape = Microsoft.Msagl.Drawing.Shape.Box;
var edge1_2 = g.AddEdgeBetweenNodes(node1, node2);
var edge2_3 = g.AddEdgeBetweenNodes(node2, node3);
// Set some labels.
node11.Label = new DTextLabel(node11) { Text = "Node 1.1" };
node12.Label = new DTextLabel(node12) { Text = "Node 1.2" };
node31.Label = new DTextLabel(node31) { Text = "Node 3.1" };
node32.Label = new DTextLabel(node32) { Text = "Node 3.2" };
node2.Label = new DTextLabel(node2) { Text = "Node 2" };
DEdge crossEdge1 = g.AddEdgeBetweenNodes(node11, node3);
crossEdge1.Label = new DTextLabel(crossEdge1, "cross edge");
DEdge crossEdge2 = g.AddEdgeBetweenNodes(node12, node31);
g.BeginLayout();
}
private void CreateDifferentiationGraph(DGraph graph)
{
DNode inNode = graph.AddNode("Di_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
DNode precursorNode = Nesting_Cell_AddNode(graph, "Di_precursor", "Precursor");
DNode earlyMeiosisNode = Nesting_Cell_AddNode(graph, "Di_early_meiosis", "Early Meiosis");
DNode meiosisNode = Nesting_Cell_AddNode(graph, "Di_meiosis", "Meiosis");
DNode gameteNode = Nesting_Cell_AddNode(graph, "Di_gamete", null);
Grid gameteContainer = new Grid();
gameteContainer.RowDefinitions.Add(new RowDefinition());
gameteContainer.RowDefinitions.Add(new RowDefinition());
gameteContainer.Children.Add(new TextBlock() { Text = "Gamete", TextAlignment = TextAlignment.Center, FontWeight = FontWeights.Bold });
gameteNode.Label = new DNestedGraphLabel(gameteNode, gameteContainer);
DGraph gameteGraph = new DGraph(gameteNode.Label as DNestedGraphLabel) { Name = "Gamete" };
Nesting_CreateGameteGraph(gameteGraph);
Grid.SetRow(gameteGraph, 1);
gameteContainer.Children.Add(gameteGraph);
(gameteNode.Label as DNestedGraphLabel).Graphs.Add(gameteGraph);
Nesting_Cell_AddEdge(graph, inNode, precursorNode, null);
Nesting_Cell_AddEdge(graph, precursorNode, earlyMeiosisNode, "GLD-1_Act\nOR\nGLD-2_Act");
Nesting_Cell_AddEdge(graph, earlyMeiosisNode, meiosisNode, "Pachytene");
Nesting_Cell_AddEdge(graph, meiosisNode, gameteNode, "MEK-2_Act\nAND\nMPK-1_Act");
}
private void Nesting_CreateGameteGraph(DGraph graph)
{
DNode inNode = graph.AddNode("Ga_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
DNode splitterNode = graph.AddNode("Ga_sp");
splitterNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
splitterNode.DrawingNode.Attr.FillColor = MsaglColor.Blue;
DNode spermNode = Nesting_Cell_AddNode(graph, "Ga_sperm", "Sperm");
DNode oocyteNode = Nesting_Cell_AddNode(graph, "Ga_oocyte", "Oocyte");
DNode matureOocyteNode = Nesting_Cell_AddNode(graph, "Ga_matureOocyte", "Mature\nOocyte");
DNode zygoteNode = Nesting_Cell_AddNode(graph, "Ga_zygote", "Zygote");
Nesting_Cell_AddEdge(graph, inNode, splitterNode, null);
Nesting_Cell_AddEdge(graph, splitterNode, spermNode, "Sperm_Effector_Act");
Nesting_Cell_AddEdge(graph, splitterNode, oocyteNode, "Oocyte_Effector_Act");
Nesting_Cell_AddEdge(graph, oocyteNode, matureOocyteNode, "Maturation");
Nesting_Cell_AddEdge(graph, matureOocyteNode, zygoteNode, "Fertilization");
}
private void Nesting_CreateProliferationGraph(DGraph graph)
{
DNode inNode = graph.AddNode("Pr_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
DNode mitosisNode = Nesting_Cell_AddNode(graph, "Pr_mitosis", null);
Grid mitosisContainer = new Grid();
mitosisContainer.RowDefinitions.Add(new RowDefinition());
mitosisContainer.RowDefinitions.Add(new RowDefinition());
mitosisContainer.Children.Add(new TextBlock() { Text = "Mitosis", TextAlignment = TextAlignment.Center, FontWeight = FontWeights.Bold });
mitosisNode.Label = new DNestedGraphLabel(mitosisNode, mitosisContainer);
DGraph mitosisGraph = new DGraph(mitosisNode.Label as DNestedGraphLabel) { Name = "Mitosis" };
Nesting_CreateMitosisGraph(mitosisGraph);
Grid.SetRow(mitosisGraph, 1);
mitosisContainer.Children.Add(mitosisGraph);
(mitosisNode.Label as DNestedGraphLabel).Graphs.Add(mitosisGraph);
DNode splitterNode = graph.AddNode("Pr_sp");
splitterNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
splitterNode.DrawingNode.Attr.FillColor = MsaglColor.Blue;
DNode meiosisNode = Nesting_Cell_AddNode(graph, "Pr_meiosis", null);
Grid meiosisContainer = new Grid();
meiosisContainer.RowDefinitions.Add(new RowDefinition());
meiosisContainer.RowDefinitions.Add(new RowDefinition());
meiosisContainer.Children.Add(new TextBlock() { Text = "Meiosis", TextAlignment = TextAlignment.Center, FontWeight = FontWeights.Bold });
meiosisNode.Label = new DNestedGraphLabel(meiosisNode, meiosisContainer);
DGraph meiosisGraph = new DGraph(meiosisNode.Label as DNestedGraphLabel) { Name = "Meiosis" };
Nesting_CreateMeiosisGraph(meiosisGraph);
Grid.SetRow(meiosisGraph, 1);
meiosisContainer.Children.Add(meiosisGraph);
(meiosisNode.Label as DNestedGraphLabel).Graphs.Add(meiosisGraph);
Nesting_Cell_AddEdge(graph, inNode, mitosisNode, null);
Nesting_Cell_AddEdge(graph, mitosisNode, splitterNode, "Early Meiosis");
DEdge splitter_g0_edge = graph.AddEdgeBetweenNodes(splitterNode, mitosisGraph.NodeMap["Mi_g0"]);
splitter_g0_edge.DrawingEdge.Attr.Color = MsaglColor.Red;
DEdge splitter_inter_edge = graph.AddEdgeBetweenNodes(splitterNode, meiosisGraph.NodeMap["Me_inter"]);
splitter_inter_edge.DrawingEdge.Attr.Color = MsaglColor.Red;//*/
}
private void Nesting_CreateMitosisGraph(DGraph graph)
{
DNode inNode = graph.AddNode("Mi_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
DNode g0Node = Nesting_Cell_AddNode(graph, "Mi_g0", "G0");
DNode cycleNode = Nesting_Cell_AddNode(graph, "Mi_cycle", null);
DGraph cycleGraph = new DGraph() { Name = "Mitosis Cycle" };
cycleGraph.ConfigureIncrementalLayout();
DNode c_G1_Node = Nesting_Cell_AddNode(cycleGraph, "Mi_cycle_G1", "G1");
DNode c_S_Node = Nesting_Cell_AddNode(cycleGraph, "Mi_cycle_S", "S");
DNode c_G2_Node = Nesting_Cell_AddNode(cycleGraph, "Mi_cycle_G2", "G2");
DNode c_M_Node = Nesting_Cell_AddNode(cycleGraph, "Mi_cycle_M", "M");
Nesting_Cell_AddEdge(cycleGraph, c_G1_Node, c_S_Node, null);
Nesting_Cell_AddEdge(cycleGraph, c_S_Node, c_G2_Node, null);
Nesting_Cell_AddEdge(cycleGraph, c_G2_Node, c_M_Node, null);
cycleNode.Label = new DNestedGraphLabel(cycleNode, cycleGraph);
Nesting_Cell_AddEdge(graph, cycleNode, g0Node, "exit cell\ncycle");
Nesting_Cell_AddEdge(graph, inNode, g0Node, null);
DEdge g0_g1_edge = graph.AddEdgeBetweenNodes(g0Node, c_G1_Node);
g0_g1_edge.DrawingEdge.Attr.Color = MsaglColor.Red;//*/
}
private DNode Nesting_Cell_AddNode(DGraph graph, string id, string label)
{
DNode ret = graph.AddNode(id);
if (label != null)
ret.Label = new DTextLabel(ret, label);
ret.DrawingNode.Attr.Color = MsaglColor.Green;
ret.DrawingNode.Attr.LineWidth = 2.0;
ret.DrawingNode.Attr.Shape = MsaglShape.Box;
ret.DrawingNode.Attr.XRadius = 5.0;
ret.DrawingNode.Attr.YRadius = 5.0;
return ret;
}
private void CreateDifferentiation(DGraph graph, DCluster differentiation)
{
var inNode = graph.AddNode("Differentiation_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
graph.AddNodeToCluster(differentiation, inNode);
var precursor = Clustering_Cell_AddNode(graph, differentiation, "Precursor", "Precursor");
var earlyMeiosis = Clustering_Cell_AddNode(graph, differentiation, "EarlyMeiosis", "Early Meiosis");
var meiosis = Clustering_Cell_AddNode(graph, differentiation, "Diff_Meiosis", "Meiosis");
var gamete = graph.AddCluster(differentiation, "Gamete");
Clustering_ApplyNodeAttributes(gamete);
CreateGamete(graph, gamete);
Clustering_Cell_AddEdge(graph, inNode, precursor, null);
Clustering_Cell_AddEdge(graph, precursor, earlyMeiosis, "GLD-1_Act\nOR\nGLD-2_Act");
Clustering_Cell_AddEdge(graph, earlyMeiosis, meiosis, "Pachytene");
Clustering_Cell_AddEdge(graph, meiosis, gamete, "MEK-2_Act\nAND\nMPK-1_Act");//*/
}
private void CreateGamete(DGraph graph, DCluster gamete)
{
var inNode = graph.AddNode("Gamete_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
graph.AddNodeToCluster(gamete, inNode);
var splitter = graph.AddNode("Gamete_Splitter");
splitter.DrawingNode.Attr.Shape = MsaglShape.Circle;
splitter.DrawingNode.Attr.FillColor = MsaglColor.Blue;
graph.AddNodeToCluster(gamete, splitter);
var sperm = Clustering_Cell_AddNode(graph, gamete, "Sperm", "Sperm");
var oocyte = Clustering_Cell_AddNode(graph, gamete, "Oocyte", "Oocyte");
var matureOocyte = Clustering_Cell_AddNode(graph, gamete, "MatureOocyte", "Mature\nOocyte");
var zygote = Clustering_Cell_AddNode(graph, gamete, "Zygote", "Zygote");
Clustering_Cell_AddEdge(graph, inNode, splitter, null);
Clustering_Cell_AddEdge(graph, splitter, sperm, "Sperm_Effector_Act");
Clustering_Cell_AddEdge(graph, splitter, oocyte, "Oocyte_Effector_Act");
Clustering_Cell_AddEdge(graph, oocyte, matureOocyte, "Maturation");
Clustering_Cell_AddEdge(graph, matureOocyte, zygote, "Fertilization");//*/
}
private void CreateProliferation(DGraph graph, DCluster proliferation)
{
var inNode = graph.AddNode("Proliferation_in");
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
graph.AddNodeToCluster(proliferation, inNode);
var splitter = graph.AddNode("Proliferation_Splitter");
splitter.DrawingNode.Attr.Shape = MsaglShape.Circle;
splitter.DrawingNode.Attr.FillColor = MsaglColor.Blue;
graph.AddNodeToCluster(proliferation, splitter);
var mitosis = graph.AddCluster(proliferation, "Mitosis");
Clustering_ApplyNodeAttributes(mitosis);
CreateMitosis(graph, mitosis);
var meiosis = graph.AddCluster(proliferation, "Meiosis");
Clustering_ApplyNodeAttributes(meiosis);
CreateMeiosis(graph, meiosis);
Clustering_Cell_AddEdge(graph, inNode, mitosis, null);
Clustering_Cell_AddEdge(graph, mitosis, splitter, "Early Meiosis");
Clustering_Cell_AddEdge(graph, splitter, graph.NodeMap["G0"], null);
Clustering_Cell_AddEdge(graph, splitter, graph.NodeMap["Inter"], null);//*/
}
private void CreateMitosis(DGraph graph, DCluster mitosis)
{
var inNode = graph.AddNode("Mitosis_In");
graph.AddNodeToCluster(mitosis, inNode);
inNode.DrawingNode.Attr.Shape = MsaglShape.Circle;
inNode.DrawingNode.Attr.FillColor = MsaglColor.Red;
var g0 = Clustering_Cell_AddNode(graph, mitosis, "G0", "G0");
var mitosis_cycle = graph.AddCluster(mitosis, "Mitosis_Cycle");
Clustering_ApplyNodeAttributes(mitosis_cycle);
var g1 = Clustering_Cell_AddNode(graph, mitosis_cycle, "G1", "G1");
var s = Clustering_Cell_AddNode(graph, mitosis_cycle, "S", "S");
var g2 = Clustering_Cell_AddNode(graph, mitosis_cycle, "G2", "G2");
var m = Clustering_Cell_AddNode(graph, mitosis_cycle, "M", "M");
Clustering_Cell_AddEdge(graph, inNode, g0, null);
Clustering_Cell_AddEdge(graph, g0, g1, null);
Clustering_Cell_AddEdge(graph, g1, s, null);
Clustering_Cell_AddEdge(graph, s, g2, null);
Clustering_Cell_AddEdge(graph, g2, m, null);
Clustering_Cell_AddEdge(graph, mitosis_cycle, g0, "exit cell\ncycle");//*/
}
private DNode Clustering_Cell_AddNode(DGraph graph, DCluster cluster, string id, string label)
{
var ret = graph.AddNode(id);
if (label != null)
ret.Label = new DTextLabel(ret, label);
graph.AddNodeToCluster(cluster, ret);
Clustering_ApplyNodeAttributes(ret);
return ret;
}