/// <summary>
/// Gets proteins with applied variants from this protein
/// </summary>
public List <ProteinWithAppliedVariants> GetVariantProteins()
{
List <SequenceVariation> uniqueEffects = SequenceVariations
.GroupBy(v => v.OriginalSequence + v.OneBasedBeginPosition.ToString() + v.VariantSequence).Select(x => x.First())
.Where(v => v.Description.Split('\t').Length >= 10) // likely a VCF line (should probably do more rigorous testing, eventually)
.OrderByDescending(v => v.OneBasedBeginPosition) // apply variants at the end of the protein sequence first
.ToList();
ProteinWithAppliedVariants variantProtein = new ProteinWithAppliedVariants(BaseSequence, this, null, null);
return(variantProtein.ApplyVariants(variantProtein, uniqueEffects));
}
/// <summary>
/// Gets proteins with applied variants from this protein
/// </summary>
public List <ProteinWithAppliedVariants> GetVariantProteins()
{
if (SequenceVariations.Count() > 0)
{
int i = 0;
int asdf = SequenceVariations.Select(v => v.Description.Split(new[] { @"\t" }, StringSplitOptions.None).Length).Max();
}
List <SequenceVariation> uniqueEffects = SequenceVariations
.GroupBy(v => v.SimpleString())
.Select(x => x.First())
.Where(v => v.Description.Split(new[] { @"\t" }, StringSplitOptions.None).Length >= 10) // likely a VCF line (should probably do more rigorous testing, eventually)
.OrderByDescending(v => v.OneBasedBeginPosition) // apply variants at the end of the protein sequence first
.ToList();
ProteinWithAppliedVariants variantProtein = new ProteinWithAppliedVariants(BaseSequence, this, null, ProteolysisProducts, OneBasedPossibleLocalizedModifications, null);
return(variantProtein.ApplyVariants(variantProtein, uniqueEffects));
}
