Beispiel #1
0
        public void PathPurger1()
        {
            const int        kmerLength = 7;
            List <ISequence> sequences  = new List <ISequence>();

            sequences.Add(new Sequence(Alphabets.DNA, "GATTCAAGGGCTGGGGG"));
            this.KmerLength = kmerLength;
            this.AddSequenceReads(sequences);
            this.CreateGraph();
            List <DeBruijnNode>  contigs = this.Graph.Nodes.ToList();
            IList <ScaffoldPath> paths   =
                new List <ScaffoldPath>();
            ScaffoldPath path = new ScaffoldPath();

            foreach (DeBruijnNode node in contigs)
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(2, 5))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(3, 5))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(6, 5))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(0, 11))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(7, 4))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(11, 0))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(2, 9))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (DeBruijnNode node in contigs.GetRange(1, 10))
            {
                path.Add(new KeyValuePair <DeBruijnNode, DeBruijnEdge>(node, null));
            }

            paths.Add(path);
            PathPurger assembler = new PathPurger();

            assembler.PurgePath(paths);
            Assert.AreEqual(paths.Count, 1);
            Assert.IsTrue(Compare(paths.First(), contigs));
        }
Beispiel #2
0
        public void PathPurger1()
        {
            const int         KmerLength      = 7;
            ISequence         sequence        = new Sequence(Alphabets.DNA, "GATTCAAGGGCTGGGGG");
            IList <ISequence> contigsSequence = SequenceToKmerBuilder.GetKmerSequences(sequence, KmerLength).ToList();
            ContigGraph       graph           = new ContigGraph();

            graph.BuildContigGraph(contigsSequence, KmerLength);
            List <Node>          contigs = graph.Nodes.ToList();
            IList <ScaffoldPath> paths   =
                new List <ScaffoldPath>();
            ScaffoldPath path = new ScaffoldPath();

            foreach (Node node in contigs)
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(2, 5))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(3, 5))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(6, 5))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(0, 11))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(7, 4))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(11, 0))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(2, 9))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            path = new ScaffoldPath();
            foreach (Node node in contigs.GetRange(1, 10))
            {
                path.Add(new KeyValuePair <Node, Edge>(node, null));
            }

            paths.Add(path);
            PathPurger assembler = new PathPurger();

            assembler.PurgePath(paths);
            Assert.AreEqual(paths.Count, 1);
            Assert.IsTrue(Compare(paths.First(), contigs));
        }