private CanvasOutput GetCanvasOutput(string sampleId, IDirectoryLocation sampleSandbox)
{
var cnvVcf = new Vcf(sampleSandbox.GetFileLocation("CNV.vcf.gz"));
var tempCnvDirectory = sampleSandbox.GetDirectoryLocation($"TempCNV_{sampleId}");
var variantFrequencies = tempCnvDirectory.GetFileLocation($"VFResults{sampleId}.txt.gz");
var variantFrequenciesBaf = tempCnvDirectory.GetFileLocation($"VFResults{sampleId}.txt.gz.baf");
IFileLocation coverageAndVariantFrequencies = sampleSandbox.GetFileLocation("CNV.CoverageAndVariantFrequency.txt");
IFileLocation tempStub = tempCnvDirectory.GetFileLocation($"{sampleId}");
IFileLocation partitioned = tempStub.AppendName(".partitioned");
return(new CanvasOutput(cnvVcf, coverageAndVariantFrequencies, variantFrequencies,
variantFrequenciesBaf, partitioned));
}
private CanvasEnrichmentOutput GetCanvasOutput(string sampleId, IDirectoryLocation sampleSandbox)
{
var cnvVcf = new Vcf(sampleSandbox.GetFileLocation("CNV.vcf.gz"));
var tempCnvDirectory = sampleSandbox.GetDirectoryLocation($"TempCNV_{sampleId}");
var variantFrequencies = tempCnvDirectory.GetFileLocation($"VFResults{sampleId}.txt.gz");
var variantFrequenciesBaf = tempCnvDirectory.GetFileLocation($"VFResults{sampleId}.txt.gz.baf");
IFileLocation coverageAndVariantFrequencies = sampleSandbox.GetFileLocation("CNV.CoverageAndVariantFrequency.txt");
IFileLocation tempStub = tempCnvDirectory.GetFileLocation($"{sampleId}");
IFileLocation partitioned = tempStub.AppendName(".partitioned");
var canvasOutput = new CanvasOutput(cnvVcf, coverageAndVariantFrequencies, variantFrequencies,
variantFrequenciesBaf, partitioned);
IFileLocation binSize = tempStub.AppendName(".binsize");
IFileLocation normalBinned = tempStub.AppendName(".normal.binned");
IFileLocation unsmoothedCnd = tempStub.AppendName(".ratio.binned.cnd");
if (!binSize.Exists)
{
binSize = null;
}
return(new CanvasEnrichmentOutput(canvasOutput, binSize, normalBinned, unsmoothedCnd));
}
public static IDirectoryLocation GetSampleOutputFolder(IDirectoryLocation analysisOutputFolder, string sampleName)
{
return(analysisOutputFolder.GetDirectoryLocation($"TempCNV_{sampleName}"));
}
