示例#1
0
        public override void SetState(YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
        {
            base.SetState(accessionOrder);

            if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(this.m_PanelSet.PanelSetId) == true)
            {
                this.m_HasPanelSetBeenOrdered        = true;
                this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_PanelSet.PanelSetId);
                if (this.m_PanelSetOrderLynchSyndromeIHC.Final == true)
                {
                    while (true)
                    {
                        if (this.HandlePPPPResults() == true)
                        {
                            break;
                        }
                        if (this.HandleNPPNResults() == true)
                        {
                            break;
                        }
                        break;
                    }
                }
            }
        }
示例#2
0
        public override bool IncludeInIHCCollection(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC)
        {
            bool result = false;

            if (panelSetOrderLynchSyndromeIHC.MLH1Result == LSEIHCResult.IntactDescription &&
                panelSetOrderLynchSyndromeIHC.MSH2Result == LSEIHCResult.LossDescription &&
                panelSetOrderLynchSyndromeIHC.MSH6Result == LSEIHCResult.IntactDescription &&
                panelSetOrderLynchSyndromeIHC.PMS2Result == LSEIHCResult.IntactDescription)
            {
                result = true;
            }
            else if (panelSetOrderLynchSyndromeIHC.MLH1Result == LSEIHCResult.IntactDescription &&
                     panelSetOrderLynchSyndromeIHC.MSH2Result == LSEIHCResult.LossDescription &&
                     panelSetOrderLynchSyndromeIHC.MSH6Result == LSEIHCResult.LossDescription &&
                     panelSetOrderLynchSyndromeIHC.PMS2Result == LSEIHCResult.IntactDescription)
            {
                result = true;
            }
            else if (panelSetOrderLynchSyndromeIHC.MLH1Result == LSEIHCResult.IntactDescription &&
                     panelSetOrderLynchSyndromeIHC.MSH2Result == LSEIHCResult.IntactDescription &&
                     panelSetOrderLynchSyndromeIHC.MSH6Result == LSEIHCResult.LossDescription &&
                     panelSetOrderLynchSyndromeIHC.PMS2Result == LSEIHCResult.IntactDescription)
            {
                result = true;
            }
            else if (panelSetOrderLynchSyndromeIHC.MLH1Result == LSEIHCResult.IntactDescription &&
                     panelSetOrderLynchSyndromeIHC.MSH2Result == LSEIHCResult.IntactDescription &&
                     panelSetOrderLynchSyndromeIHC.MSH6Result == LSEIHCResult.IntactDescription &&
                     panelSetOrderLynchSyndromeIHC.PMS2Result == LSEIHCResult.LossDescription)
            {
                result = true;
            }
            return(result);
        }
示例#3
0
 public virtual void SetResults(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrder)
 {
     panelSetOrder.ResultCode = this.m_ResultCode;
     panelSetOrder.MLH1Result = this.m_MLH1Result.Description;
     panelSetOrder.MSH2Result = this.m_MSH2Result.Description;
     panelSetOrder.MSH6Result = this.m_MSH6Result.Description;
     panelSetOrder.PMS2Result = this.m_PMS2Result.Description;
 }
 public LynchSyndromeIHCPanelResultPath(string reportNo,
     YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
     YellowstonePathology.UI.Navigation.PageNavigator pageNavigator,
     System.Windows.Window window)
     : base(pageNavigator, window)
 {
     this.m_AccessionOrder = accessionOrder;
     this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
 }
 public LynchSyndromeIHCPanelResultPath(string reportNo,
                                        YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
                                        YellowstonePathology.UI.Navigation.PageNavigator pageNavigator,
                                        System.Windows.Window window)
     : base(pageNavigator, window)
 {
     this.m_AccessionOrder = accessionOrder;
     this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
 }
        public LynchSyndromeIHCPanelResultPage(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC,
                                               YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
                                               YellowstonePathology.Business.User.SystemIdentity systemIdentity)
        {
            this.m_PanelSetOrderLynchSyndromeIHC = panelSetOrderLynchSyndromeIHC;
            this.m_AccessionOrder = accessionOrder;
            this.m_SystemIdentity = systemIdentity;

            this.m_PageHeaderText = "Lynch Syndrome IHC Results For: " + this.m_AccessionOrder.PatientDisplayName + " (" + this.m_PanelSetOrderLynchSyndromeIHC.ReportNo + ")";

            YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetByAliquotOrderId(this.m_PanelSetOrderLynchSyndromeIHC.OrderedOnId);
            YellowstonePathology.Business.Test.AliquotOrder            aliquotOrder  = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(this.m_PanelSetOrderLynchSyndromeIHC.OrderedOnId);
            this.m_OrderedOnDescription = specimenOrder.Description + ": " + aliquotOrder.Label;

            InitializeComponent();

            DataContext = this;
        }
        public LynchSyndromeIHCPanelResultPage(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC,
			YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
			YellowstonePathology.Business.User.SystemIdentity systemIdentity)
        {
            this.m_PanelSetOrderLynchSyndromeIHC = panelSetOrderLynchSyndromeIHC;
            this.m_AccessionOrder = accessionOrder;
            this.m_SystemIdentity = systemIdentity;

            this.m_PageHeaderText = "Lynch Syndrome IHC Results For: " + this.m_AccessionOrder.PatientDisplayName + " (" + this.m_PanelSetOrderLynchSyndromeIHC.ReportNo + ")";

            YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetByAliquotOrderId(this.m_PanelSetOrderLynchSyndromeIHC.OrderedOnId);
            YellowstonePathology.Business.Test.AliquotOrder aliquotOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(this.m_PanelSetOrderLynchSyndromeIHC.OrderedOnId);
            this.m_OrderedOnDescription = specimenOrder.Description + ": " + aliquotOrder.Label;

            InitializeComponent();

            DataContext = this;
        }
示例#8
0
        public override void SetState(YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
        {
            base.SetState(accessionOrder);

            if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(this.m_PanelSet.PanelSetId) == true)
            {
                this.m_HasPanelSetBeenOrdered = true;
                this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_PanelSet.PanelSetId);
                if (this.m_PanelSetOrderLynchSyndromeIHC.Final == true)
                {
                    while (true)
                    {
                        if (this.HandlePPPPResults() == true) break;
                        if (this.HandleNPPNResults() == true) break;
                        break;
                    }
                }
            }
        }
示例#9
0
        protected string BuildLossResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
        {
            string result = null;

            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
            {
                YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
                result = "Loss of nuclear expression of ";
                List <string> results = new List <string>();
                if (panelSetOrderLynchSyndromeIHC.MLH1Result == LSEIHCResult.LossDescription)
                {
                    results.Add("MLH1");
                }
                if (panelSetOrderLynchSyndromeIHC.MSH2Result == LSEIHCResult.LossDescription)
                {
                    results.Add("MSH2");
                }
                if (panelSetOrderLynchSyndromeIHC.MSH6Result == LSEIHCResult.LossDescription)
                {
                    results.Add("MSH6");
                }
                if (panelSetOrderLynchSyndromeIHC.PMS2Result == LSEIHCResult.LossDescription)
                {
                    results.Add("PMS2");
                }

                var joinedResults = string.Join(", ", results);
                if (results.Count > 1)
                {
                    int posOfLastComma = joinedResults.LastIndexOf(",");
                    joinedResults = joinedResults.Remove(posOfLastComma, 1);
                    joinedResults = joinedResults.Insert(posOfLastComma, " and");
                }

                string multiLoss = "proteins. ";
                if (results.Count == 1)
                {
                    multiLoss = "protein. ";
                }
                result = result + joinedResults + " mismatch repair " + multiLoss;
            }
            return(result);
        }
示例#10
0
 public virtual bool IncludeInIHCCollection(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC)
 {
     throw new Exception("IncludeInIHCCollection Not implemented  in LSERule.");
 }
示例#11
0
        protected Rules.MethodResult HasFinalIHCResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
        {
            Rules.MethodResult result = new Rules.MethodResult();
            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
            {
                YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
                if (panelSetOrderLynchSyndromeIHC.Final == false)
                {
                    result.Success = false;
                    result.Message = "Unable to set results as the " + panelSetLynchSyndromeIHCPanel.PanelSetName + " is not final.";
                }
            }
            else
            {
                result.Success = false;
                result.Message = "Unable to set results as a " + panelSetLynchSyndromeIHCPanel.PanelSetName + " must be ordered.";
            }

            return(result);
        }
示例#12
0
        public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
                                                     ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
        {
            this.m_SpecimenOrder         = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
            this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
            this.m_SurgicalSpecimen      = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);

            bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;

            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_LSEIHCIsOrdered = true;
                this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
                this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_MLHIsOrdered = true;
                this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_BRAFV600EKIsOrdered = true;
                this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASStandardIsOrdered = true;
                this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon23MutationIsOrdered = true;
                this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon4MutationIsOrdered = true;
                this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_NRASMutationAnalysisIsOrdered = true;
                this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_RASRAFIsOrdered      = true;
                this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }
        }
示例#13
0
        public override void Render()
        {
            int molecularTestCount = 0;

            this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\LynchSyndromeEvaluation.6.xml";
            this.OpenTemplate();
            this.SetDemographicsV2();
            this.SetReportDistribution();

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_PanelSetOrder;
            base.ReplaceText("report_interpretation", panelSetOrderLynchSyndromeEvaluation.Interpretation);
            base.ReplaceText("report_comment", panelSetOrderLynchSyndromeEvaluation.Comment);

            YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
            this.ReplaceText("specimen_description", specimenOrder.Description);

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
            if (panelSetOrderLynchSyndromeIHC != null)
            {
                base.ReplaceText("mlh1_result", panelSetOrderLynchSyndromeIHC.MLH1Result);
                base.ReplaceText("msh2_result", panelSetOrderLynchSyndromeIHC.MSH2Result);
                base.ReplaceText("msh6_result", panelSetOrderLynchSyndromeIHC.MSH6Result);
                base.ReplaceText("pms2_result", panelSetOrderLynchSyndromeIHC.PMS2Result);
            }

            if (panelSetOrderLynchSyndromeEvaluation.BRAFIsIndicated == true)
            {
                molecularTestCount += 1;
                if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(18) == true) //BRAF
                {
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest      brafV600EKTest    = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId);

                    base.ReplaceText("braf_result", panelSetOrderBraf.Result);
                    base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
                }
            }
            else
            {
                this.DeleteRow("braf_result");
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId) == true)
            {
                molecularTestCount += 1;
                YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId);
                base.ReplaceText("mlh1methylation_result", panelSetOrderMLH1MethylationAnalysis.Result);
                base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
            }
            else
            {
                this.DeleteRow("mlh1methylation_result");
            }

            if (molecularTestCount == 0)
            {
                this.DeleteRow("molecular_analysis_header");
            }

            base.ReplaceText("report_references", panelSetOrderLynchSyndromeEvaluation.References);
            base.ReplaceText("report_method", panelSetOrderLynchSyndromeEvaluation.Method);
            base.ReplaceText("pathologist_signature", panelSetOrderLynchSyndromeEvaluation.Signature);

            this.SaveReport();
        }
        public override void Render()
        {
            Business.Test.LynchSyndrome.LynchSyndromeEvaluationTest lynchSyndromeEvaluationTest = new LynchSyndromeEvaluationTest();

            int molecularTestCount = 0;

            this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\LynchSyndromeEvaluation.2.xml";
            this.OpenTemplate();
            this.SetDemographicsV2();
            this.SetReportDistribution();
            YellowstonePathology.Business.Amendment.Model.AmendmentCollection amendmentCollection = this.m_AccessionOrder.AmendmentCollection.GetAmendmentsForReport(m_PanelSetOrder.ReportNo);
            this.SetAmendments(amendmentCollection);

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_PanelSetOrder;
            base.ReplaceText("report_result", panelSetOrderLynchSyndromeEvaluation.Result);
            base.ReplaceText("report_interpretation", panelSetOrderLynchSyndromeEvaluation.Interpretation);

            YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
            this.ReplaceText("specimen_description", specimenOrder.Description);

            string collectionDateTimeString = YellowstonePathology.Business.Helper.DateTimeExtensions.CombineDateAndTime(specimenOrder.CollectionDate, specimenOrder.CollectionTime);

            this.SetXmlNodeData("date_time_collected", collectionDateTimeString);

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
            if (panelSetOrderLynchSyndromeIHC != null)
            {
                base.ReplaceText("mlh1_result", panelSetOrderLynchSyndromeIHC.MLH1Result);
                base.ReplaceText("msh2_result", panelSetOrderLynchSyndromeIHC.MSH2Result);
                base.ReplaceText("msh6_result", panelSetOrderLynchSyndromeIHC.MSH6Result);
                base.ReplaceText("pms2_result", panelSetOrderLynchSyndromeIHC.PMS2Result);
            }

            if (panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth == true)
            {
                molecularTestCount += 1;
                YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTest brafMutationAnlaysis = new BRAFMutationAnalysis.BRAFMutationAnalysisTest();
                YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest   brafV600EKTest  = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
                YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest rasRAFPanelTest = new YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest();

                if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
                {
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
                    base.ReplaceText("braf_result", panelSetOrderBraf.Result);
                    base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
                }
                else if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(brafMutationAnlaysis.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
                {
                    YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafMutationAnlaysis.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
                    base.ReplaceText("braf_result", panelSetOrderBraf.Result);
                    base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
                }
                else if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
                {
                    YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder panelSetOrderRASRAF = (YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
                    base.ReplaceText("braf_result", panelSetOrderRASRAF.BRAFResult);
                    base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
                }
            }
            else
            {
                this.DeleteRow("braf_result");
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
            {
                molecularTestCount += 1;
                YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
                base.ReplaceText("mlh1methylation_result", panelSetOrderMLH1MethylationAnalysis.Result);
                base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
            }
            else
            {
                this.DeleteRow("mlh1methylation_result");
            }

            if (molecularTestCount == 0)
            {
                this.DeleteRow("molecular_analysis_header");
            }

            base.ReplaceText("report_references", panelSetOrderLynchSyndromeEvaluation.ReportReferences);
            base.ReplaceText("report_method", panelSetOrderLynchSyndromeEvaluation.Method);
            base.ReplaceText("pathologist_signature", panelSetOrderLynchSyndromeEvaluation.Signature);


            base.ReplaceText("summary_location_performed", this.m_AccessionOrder.PanelSetOrderCollection.GetLocationPerformedSummary(lynchSyndromeEvaluationTest.PanelSetIDList));

            this.SaveReport();
        }
        public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
			ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
        {
            this.m_SpecimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
            this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
            this.m_SurgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);

            bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;
            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_LSEIHCIsOrdered = true;
                this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
                this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_MLHIsOrdered = true;
                this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_BRAFV600EKIsOrdered = true;
                this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASStandardIsOrdered = true;
                this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon23MutationIsOrdered = true;
                this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon4MutationIsOrdered = true;
                this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_NRASMutationAnalysisIsOrdered = true;
                this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
            if(accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_RASRAFIsOrdered = true;
                this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }
        }
示例#16
0
        public static LSEResult GetResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
        {
            LSEResult result = new LSEResult();

            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest     panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId);
            if (panelSetOrderLynchSyndromeIHC != null)
            {
                panelSetOrderLynchSyndromeIHC.SetSummaryResult(result);
            }

            if (panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated == true)
            {
                YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
                if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
                {
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
                    panelSetOrderBraf.SetSummaryResult(result);
                }
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
            {
                YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
                panelSetOrderMLH1MethylationAnalysis.SetSummaryResult(result);
            }

            return(result);
        }
        public override void Render()
        {
            this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\LynchSyndromeIHCPanel.5.xml";
            base.OpenTemplate();

            this.SetDemographicsV2();
            this.SetReportDistribution();
            this.SetCaseHistory();

            YellowstonePathology.Business.Document.AmendmentSection amendmentSection = new YellowstonePathology.Business.Document.AmendmentSection();
            amendmentSection.SetAmendment(m_PanelSetOrder.AmendmentCollection, this.m_ReportXml, this.m_NameSpaceManager, true);

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrder = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_PanelSetOrder;

            YellowstonePathology.Business.Test.AliquotOrder            aliquotOrder  = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(panelSetOrder.OrderedOnId);
            YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrder.OrderedOn, panelSetOrder.OrderedOnId);

            string specimenDescription = specimenOrder.Description + ", Block " + aliquotOrder.Label;

            this.ReplaceText("specimen_description", specimenDescription);

            string collectionDateTimeString = YellowstonePathology.Business.Helper.DateTimeExtensions.CombineDateAndTime(specimenOrder.CollectionDate, specimenOrder.CollectionTime);

            this.SetXmlNodeData("date_time_collected", collectionDateTimeString);

            this.SetXmlNodeData("mlh1_result", panelSetOrder.MLH1Result);
            this.SetXmlNodeData("msh2_result", panelSetOrder.MSH2Result);
            this.SetXmlNodeData("msh6_result", panelSetOrder.MSH6Result);
            this.SetXmlNodeData("pms2_result", panelSetOrder.PMS2Result);

            this.ReplaceText("report_date", BaseData.GetShortDateString(this.m_PanelSetOrder.FinalDate));
            this.ReplaceText("pathologist_signature", this.m_PanelSetOrder.Signature);

            this.SaveReport();
        }
        public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
                                                     ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
        {
            this.m_SpecimenOrder         = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
            this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
            this.m_SurgicalSpecimen      = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);

            bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;

            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_LSEIHCIsOrdered = true;
                this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
                this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
            }
            else
            {
                YellowstonePathology.Business.Domain.PatientHistory patientHistory = YellowstonePathology.Business.Gateway.AccessionOrderGateway.GetPatientHistory(accessionOrder.PatientId);
                if (patientHistory.PanelSetIdExists(102) == true)
                {
                    YellowstonePathology.Business.Domain.PatientHistoryResult patientHistoryResult = patientHistory.GetByPanelSetId(102);
                    YellowstonePathology.Business.Test.AccessionOrder         lseIHCAccessionOrder = Business.Persistence.DocumentGateway.Instance.GetAccessionOrderByMasterAccessionNo(patientHistoryResult.MasterAccessionNo);
                    this.m_LSEIHCIsOrdered = true;

                    if (this.m_PanelSetOrderSurgical.MasterAccessionNo == patientHistoryResult.MasterAccessionNo)
                    {
                        this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
                    }
                    else
                    {
                        this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
                    }

                    this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
                }
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_MLHIsOrdered = true;
                this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_BRAFV600EKIsOrdered = true;
                this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASStandardIsOrdered = true;
                this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon23MutationIsOrdered = true;
                this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon4MutationIsOrdered = true;
                this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_NRASMutationAnalysisIsOrdered = true;
                this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_RASRAFIsOrdered      = true;
                this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_SurgicalSpecimenCollection = new YellowstonePathology.Business.Test.Surgical.SurgicalSpecimenCollection();
            foreach (YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder in accessionOrder.SpecimenOrderCollection)
            {
                YellowstonePathology.Business.Test.Surgical.SurgicalSpecimen surgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(specimenOrder.SpecimenOrderId);
                if (surgicalSpecimen != null)
                {
                    this.m_SurgicalSpecimenCollection.Add(surgicalSpecimen);
                }
            }

            this.m_PanelSetOrderLynchSyndromeIHCCollection = new Collection <LynchSyndrome.PanelSetOrderLynchSyndromeIHC>();
            this.m_MolecularTestOrderCollection            = new PanelSetOrderCollection();
            foreach (YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder in accessionOrder.PanelSetOrderCollection)
            {
                if (panelSetOrder is YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)
                {
                    this.m_PanelSetOrderLynchSyndromeIHCCollection.Add((YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)panelSetOrder);
                }
                else
                {
                    if (panelSetOrder is LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis ||
                        panelSetOrder is KRASStandard.KRASStandardTestOrder ||
                        panelSetOrder is KRASExon23Mutation.KRASExon23MutationTestOrder ||
                        panelSetOrder is KRASExon4Mutation.KRASExon4MutationTestOrder ||
                        panelSetOrder is BRAFV600EK.BRAFV600EKTestOrder ||
                        panelSetOrder is NRASMutationAnalysis.NRASMutationAnalysisTestOrder ||
                        panelSetOrder is RASRAFPanel.RASRAFPanelTestOrder)
                    {
                        this.m_MolecularTestOrderCollection.Add(panelSetOrder);
                    }
                }
            }

            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == false)
            {
                YellowstonePathology.Business.Domain.PatientHistory patientHistory = YellowstonePathology.Business.Gateway.AccessionOrderGateway.GetPatientHistory(accessionOrder.PatientId);
                if (patientHistory.PanelSetIdExists(102) == true)
                {
                    YellowstonePathology.Business.Domain.PatientHistoryResult patientHistoryResult = patientHistory.GetByPanelSetId(102);
                    YellowstonePathology.Business.Test.AccessionOrder         lseIHCAccessionOrder = Business.Persistence.DocumentGateway.Instance.GetAccessionOrderByMasterAccessionNo(patientHistoryResult.MasterAccessionNo);
                    this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
                    this.m_PanelSetOrderLynchSyndromeIHCCollection.Add(m_PanelSetOrderLynchSyndromeIHC);
                }
            }
        }
示例#19
0
        public override void ToXml(XElement document)
        {
            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_ReportNo);

            this.AddHeader(document, panelSetOrderLynchSyndromeEvaluation, "Lynch Syndrome Evaluation");
            this.AddNextObxElement("", document, "F");

            this.AddNextObxElement("Interpretation:", document, "F");
            this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.Interpretation, document, "F");
            this.AddNextObxElement("", document, "F");

            this.HandleLongString("Comment:", document, "F");
            this.AddNextObxElement(panelSetOrderLynchSyndromeEvaluation.Comment, document, "F");
            this.AddNextObxElement("", document, "F");

            this.AddNextObxElement("Pathologist: " + panelSetOrderLynchSyndromeEvaluation.Signature, document, "F");
            if (panelSetOrderLynchSyndromeEvaluation.FinalTime.HasValue == true)
            {
                this.AddNextObxElement("E-signed " + panelSetOrderLynchSyndromeEvaluation.FinalTime.Value.ToString("MM/dd/yyyy HH:mm"), document, "F");
            }
            this.AddNextObxElement("", document, "F");
            this.AddAmendments(document);

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
            if (panelSetOrderLynchSyndromeIHC != null)
            {
                this.AddNextObxElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document, "F");
                this.AddNextObxElement("MLH1: " + panelSetOrderLynchSyndromeIHC.MLH1Result, document, "F");
                this.AddNextObxElement("MSH2: " + panelSetOrderLynchSyndromeIHC.MSH2Result, document, "F");
                this.AddNextObxElement("MSH6: " + panelSetOrderLynchSyndromeIHC.MSH6Result, document, "F");
                this.AddNextObxElement("PMS2: " + panelSetOrderLynchSyndromeIHC.PMS2Result, document, "F");
                this.AddNextObxElement("", document, "F");
            }

            if (panelSetOrderLynchSyndromeEvaluation.BRAFIsIndicated == true)
            {
                this.AddNextObxElement("Molecular Analysis", document, "F");
                this.AddNextObxElement("", document, "F");

                if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(18) == true) //BRAF
                {
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest      brafV600EKTest    = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);

                    this.AddNextObxElement("BRAF V600E Mutation by PCR: " + panelSetOrderBraf.ReportNo, document, "F");
                    this.AddNextObxElement("Result: " + panelSetOrderBraf.Result, document, "F");
                    this.AddNextObxElement("", document, "F");
                }
            }

            YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
            this.AddNextObxElement("Specimem: " + specimenOrder.Description, document, "F");
            this.AddNextObxElement("", document, "F");

            this.AddNextObxElement("Method: ", document, "F");
            this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.Method, document, "F");
            this.AddNextObxElement("", document, "F");

            this.AddNextObxElement("References: ", document, "F");
            this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.References, document, "F");
            this.AddNextObxElement("", document, "F");
        }
示例#20
0
        private static LSERuleCollection GetIHCCollection(LSERuleCollection lseRuleCollection, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
        {
            LSERuleCollection result = new LSERuleCollection();

            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            foreach (LSERule lseRule in lseRuleCollection)
            {
                if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
                {
                    YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
                    if (panelSetOrderLynchSyndromeIHC.Final == true)
                    {
                        if (lseRule.IncludeInIHCCollection(panelSetOrderLynchSyndromeIHC) == true)
                        {
                            result.Add(lseRule);
                        }
                    }
                    else
                    {
                        result.Add(lseRule);
                    }
                }
                else
                {
                    result.Add(lseRule);
                }
            }
            return(result);
        }
        public ComprehensiveColonCancerProfileResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
			ComprehensiveColonCancerProfile comprehensiveColonCancerProfile)
        {
            this.m_SpecimenOrder = accessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(comprehensiveColonCancerProfile.OrderedOnId);
            this.m_PanelSetOrderSurgical = (YellowstonePathology.Business.Test.Surgical.SurgicalTestOrder)accessionOrder.PanelSetOrderCollection.GetSurgical();
            this.m_SurgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(this.m_SpecimenOrder.SpecimenOrderId);

            bool restrictToOrderedOn = !comprehensiveColonCancerProfile.IncludeTestsPerformedOnOtherBlocks;
            YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_LSEIHCIsOrdered = true;
                this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
                this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
            }
            else
            {
                YellowstonePathology.Business.Domain.PatientHistory patientHistory = YellowstonePathology.Business.Gateway.AccessionOrderGateway.GetPatientHistory(accessionOrder.PatientId);
                if(patientHistory.PanelSetIdExists(102) == true)
                {
                    YellowstonePathology.Business.Domain.PatientHistoryResult patientHistoryResult = patientHistory.GetByPanelSetId(102);
                    YellowstonePathology.Business.Test.AccessionOrder lseIHCAccessionOrder = Business.Persistence.DocumentGateway.Instance.GetAccessionOrderByMasterAccessionNo(patientHistoryResult.MasterAccessionNo);
                    this.m_LSEIHCIsOrdered = true;
                    this.m_PanelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)lseIHCAccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
                    this.m_IHCResult = YellowstonePathology.Business.Test.LynchSyndrome.IHCResult.CreateResultFromResultCode(this.m_PanelSetOrderLynchSyndromeIHC.ResultCode);
                }
            }

            YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_MLHIsOrdered = true;
                this.m_PanelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_BRAFV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_BRAFV600EKIsOrdered = true;
                this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASStandardTest = new YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASStandardIsOrdered = true;
                this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon23MutationTest = new KRASExon23Mutation.KRASExon23MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon23MutationIsOrdered = true;
                this.m_KRASExon23MutationTestOrder = (KRASExon23Mutation.KRASExon23MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon23MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_KRASExon4MutationTest = new KRASExon4Mutation.KRASExon4MutationTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_KRASExon4MutationIsOrdered = true;
                this.m_KRASExon4MutationTestOrder = (KRASExon4Mutation.KRASExon4MutationTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASExon4MutationTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_NRASMutationAnalysisTest = new NRASMutationAnalysis.NRASMutationAnalysisTest();
            if (accessionOrder.PanelSetOrderCollection.Exists(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_NRASMutationAnalysisIsOrdered = true;
                this.m_NRASMutationAnalysisTestOrder = (NRASMutationAnalysis.NRASMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_NRASMutationAnalysisTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_RASRAFPanelTest = new RASRAFPanel.RASRAFPanelTest();
            if(accessionOrder.PanelSetOrderCollection.Exists(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn) == true)
            {
                this.m_RASRAFIsOrdered = true;
                this.m_RASRAFPanelTestOrder = (RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_RASRAFPanelTest.PanelSetId, comprehensiveColonCancerProfile.OrderedOnId, restrictToOrderedOn);
            }

            this.m_SurgicalSpecimenCollection = new YellowstonePathology.Business.Test.Surgical.SurgicalSpecimenCollection();
            foreach (YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder in accessionOrder.SpecimenOrderCollection)
            {
                YellowstonePathology.Business.Test.Surgical.SurgicalSpecimen surgicalSpecimen = this.m_PanelSetOrderSurgical.SurgicalSpecimenCollection.GetBySpecimenOrderId(specimenOrder.SpecimenOrderId);
                if (surgicalSpecimen != null)
                {
                    this.m_SurgicalSpecimenCollection.Add(surgicalSpecimen);
                }
            }

            this.m_PanelSetOrderLynchSyndromeIHCCollection = new Collection<LynchSyndrome.PanelSetOrderLynchSyndromeIHC>();
            this.m_MolecularTestOrderCollection = new PanelSetOrderCollection();
            foreach(YellowstonePathology.Business.Test.PanelSetOrder panelSetOrder in accessionOrder.PanelSetOrderCollection)
            {
                if(panelSetOrder is YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)
                {
                    this.m_PanelSetOrderLynchSyndromeIHCCollection.Add((YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)panelSetOrder);
                }
                else
                {
                    if(panelSetOrder is LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis ||
                        panelSetOrder is KRASStandard.KRASStandardTestOrder ||
                        panelSetOrder is KRASExon23Mutation.KRASExon23MutationTestOrder ||
                        panelSetOrder is KRASExon4Mutation.KRASExon4MutationTestOrder ||
                        panelSetOrder is BRAFV600EK.BRAFV600EKTestOrder ||
                        panelSetOrder is NRASMutationAnalysis.NRASMutationAnalysisTestOrder ||
                        panelSetOrder is RASRAFPanel.RASRAFPanelTestOrder)
                    {
                        this.m_MolecularTestOrderCollection.Add(panelSetOrder);
                    }
                }
            }
        }
        public override void ToXml(XElement document)
        {
            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrder = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(106);

            this.AddCompanyHeader(document);
            this.AddBlankNteElement(document);

            this.AddNextNteElement("Lynch Syndrome Evaluation", document);
            this.AddNextNteElement("Master Accession #: " + panelSetOrder.MasterAccessionNo, document);
            this.AddNextNteElement("Report #: " + panelSetOrder.ReportNo, document);
            this.AddBlankNteElement(document);

            this.AddNextNteElement("Interpretation: ", document);
            this.HandleLongString(panelSetOrder.Interpretation, document);
            this.AddBlankNteElement(document);

            this.AddNextNteElement("Comment: ", document);
            this.HandleLongString(panelSetOrder.Comment, document);
            this.AddBlankNteElement(document);

            YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
            if (panelSetOrderLynchSyndromeIHC != null)
            {
                this.AddNextNteElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document);
                this.AddNextNteElement("MLH1: " + panelSetOrderLynchSyndromeIHC.MLH1Result, document);
                this.AddNextNteElement("MSH2: " + panelSetOrderLynchSyndromeIHC.MSH2Result, document);
                this.AddNextNteElement("MSH6: " + panelSetOrderLynchSyndromeIHC.MSH6Result, document);
                this.AddNextNteElement("PMS2: " + panelSetOrderLynchSyndromeIHC.PMS2Result, document);
                this.AddBlankNteElement(document);
            }

            if (panelSetOrder.BRAFIsIndicated == true)
            {
                this.AddNextNteElement("Molecular Analysis", document);
                this.AddBlankNteElement(document);

                if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(18) == true)                 //BRAF
                {
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest      brafV600EKTest    = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
                    YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId);

                    this.AddNextNteElement("BRAF V600E Mutation by PCR: " + panelSetOrderBraf.ReportNo, document);
                    this.AddNextNteElement("Result: " + panelSetOrderBraf.Result, document);
                    this.AddBlankNteElement(document);
                }
            }

            this.AddNextNteElement("Method: ", document);
            this.HandleLongString(panelSetOrder.Method, document);
            this.AddBlankNteElement(document);

            this.AddNextNteElement("References: ", document);
            this.HandleLongString(panelSetOrder.References, document);
            this.AddBlankNteElement(document);
        }