public override void GlobalContext()
{
base.GlobalContext();
_protocol = DomainFactoryForSpecs.CreateStandardIVProtocol();
_population = DomainFactoryForSpecs.CreateDefaultPopulation(_individual);
_simulation = DomainFactoryForSpecs.CreateSimulationWith(_population, _compound, _protocol, allowAging: true) as PopulationSimulation;
}
public override void GlobalContext()
{
base.GlobalContext();
_iv = DomainFactoryForSpecs.CreateStandardIVProtocol();
_compound = DomainFactoryForSpecs.CreateStandardCompound();
_individual = DomainFactoryForSpecs.CreateStandardIndividual(CoreConstants.Population.Preterm);
_population = DomainFactoryForSpecs.CreateDefaultPopulation(_individual);
_entityPathResolver = IoC.Resolve <IEntityPathResolver>();
_buildConfigurationTask = IoC.Resolve <IBuildConfigurationTask>();
}
private bool createPopulation(string populationName)
{
try
{
var individual = DomainFactoryForSpecs.CreateStandardIndividual(populationName);
var population = DomainFactoryForSpecs.CreateDefaultPopulation(individual);
return(true);
}
catch (Exception)
{
return(false);
}
}
public override void GlobalContext()
{
base.GlobalContext();
var diseaseStateRepository = IoC.Resolve <IDiseaseStateRepository>();
var diseaseState = diseaseStateRepository.FindByName(CoreConstants.DiseaseStates.CKD);
_individual.OriginData.DiseaseState = diseaseState;
var param = diseaseState.Parameter(CKDDiseaseStateImplementation.TARGET_GFR);
_individual.OriginData.AddDiseaseStateParameter(new OriginDataParameter {
Name = param.Name, Value = param.Value, Unit = param.DisplayUnitName()
});
_protocol = DomainFactoryForSpecs.CreateStandardIVProtocol();
_population = DomainFactoryForSpecs.CreateDefaultPopulation(_individual);
_simulation = DomainFactoryForSpecs.CreateSimulationWith(_population, _compound, _protocol) as PopulationSimulation;
}
private void runPopulationSimulationFor(string populationName, List <string> errors)
{
try
{
var individual = DomainFactoryForSpecs.CreateStandardIndividual(populationName);
var population = DomainFactoryForSpecs.CreateDefaultPopulation(individual);
var simulation = DomainFactoryForSpecs.CreateSimulationWith(population, _compound, _protocol) as PopulationSimulation;
var simulationEngine = IoC.Resolve <ISimulationEngine <PopulationSimulation> >();
var simSettingsRetriever = IoC.Resolve <ISimulationSettingsRetriever>();
simSettingsRetriever.CreatePKSimDefaults(simulation);
simulationEngine.Run(simulation);
simulation.HasResults.ShouldBeTrue();
}
catch (Exception ex)
{
var errorMsg = $"Population simulation for the population '{populationName}' failed: {ex.ToString()}";
errors.Add(errorMsg);
}
}
private async Task runPopulationSimulationFor(string populationName, List <string> errors)
{
try
{
var individual = DomainFactoryForSpecs.CreateStandardIndividual(populationName);
var population = DomainFactoryForSpecs.CreateDefaultPopulation(individual);
var simulation = DomainFactoryForSpecs.CreateSimulationWith(population, _compound, _protocol) as PopulationSimulation;
var simulationEngine = IoC.Resolve <IPopulationSimulationEngine>();
var simSettingsRetriever = IoC.Resolve <ISimulationSettingsRetriever>();
simSettingsRetriever.CreatePKSimDefaults(simulation);
var result = await simulationEngine.RunAsync(simulation, _simulationRunOptions);
if (result.Errors.Any())
{
errors.Add($"Population simulation for the population '{populationName}' failed: {result.Errors.Select(x => x.ErrorMessage).ToString("\n")}");
}
}
catch (Exception ex)
{
var errorMsg = $"Population simulation for the population '{populationName}' failed: {ex.ToString()}";
errors.Add(errorMsg);
}
}