protected void ManipulatePdf(String dest)
{
PdfDocument pdfDoc = new PdfDocument(new PdfReader(SRC), new PdfWriter(dest));
PdfPage page = pdfDoc.GetFirstPage();
PdfAnnotation sticky = page.GetAnnotations()[0];
Rectangle stickyRectangle = sticky.GetRectangle().ToRectangle();
PdfAnnotation replySticky = new PdfTextAnnotation(stickyRectangle)
.SetStateModel(new PdfString("Review"))
.SetState(new PdfString("Accepted"))
.SetIconName(new PdfName("Comment"))
// This method sets an annotation to which the current annotation is "in reply".
// Both annotations shall be on the same page of the document.
.SetInReplyTo(sticky)
// This method sets the text label that will be displayed in the title bar of the annotation's pop-up window
// when open and active. This entry shall identify the user who added the annotation.
.SetText(new PdfString("Bruno"))
// This method sets the text that will be displayed for the annotation or the alternate description,
// if this type of annotation does not display text.
.SetContents("Accepted by Bruno")
// This method sets a complete set of enabled and disabled flags at once. If not set specifically
// the default value is 0.
// The argument is an integer interpreted as set of one-bit flags
// specifying various characteristics of the annotation.
.SetFlags(sticky.GetFlags() + PdfAnnotation.HIDDEN);
pdfDoc.GetFirstPage().AddAnnotation(replySticky);
pdfDoc.Close();
}