Made available on NuGet: https://www.nuget.org/packages/Bio.VCF.ajc/.

A CSharp Parser for VCF Files. Can iterate over VCF files and provides typed access to all of the relavent information as well as data validation.

Simple Usage Example:

string fname = @"MyFile.vcf";
VCFParser vcp = new VCFParser(fname);
var myData=vcp.Where(x=>x.NoCallCount <20 && x.Biallelic).ToList();