public LynchSyndromeEvaluationResultPage(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.Business.User.SystemIdentity systemIdentity,
System.Windows.Visibility backButtonVisibility) : base(panelSetOrderLynchSyndromeEvaluation, accessionOrder)
{
this.m_PanelSetOrderLynchSyndromeEvaluation = panelSetOrderLynchSyndromeEvaluation;
this.m_AccessionOrder = accessionOrder;
this.m_SystemIdentity = systemIdentity;
this.m_BackButtonVisibility = backButtonVisibility;
this.m_LSETypeCollection = new Business.Test.LynchSyndrome.LSETypeCollection();
this.m_PageHeaderText = "Lynch Syndrome Evaluation Results For: " + this.m_AccessionOrder.PatientDisplayName + " (" + this.m_PanelSetOrderLynchSyndromeEvaluation.ReportNo + ")";
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(this.m_PanelSetOrderLynchSyndromeEvaluation.OrderedOnId);
YellowstonePathology.Business.Test.AliquotOrder aliquotOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(this.m_PanelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.m_OrderedOnDescription = specimenOrder.Description;
if (aliquotOrder != null)
{
this.m_OrderedOnDescription += ": " + aliquotOrder.Label;
}
this.FillLSERuleCollection();
InitializeComponent();
DataContext = this;
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonBack);
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonNext);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockShowDocument);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockUnfinalResults);
}
public LynchSyndromeEvaluationResultPage(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.Business.User.SystemIdentity systemIdentity,
System.Windows.Visibility backButtonVisibility)
{
this.m_PanelSetOrderLynchSyndromeEvaluation = panelSetOrderLynchSyndromeEvaluation;
this.m_AccessionOrder = accessionOrder;
this.m_SystemIdentity = systemIdentity;
this.m_BackButtonVisibility = backButtonVisibility;
this.m_LSETypeCollection = new Business.Test.LynchSyndrome.LSETypeCollection();
this.m_PageHeaderText = "Lynch Syndrome Evaluation Results For: " + this.m_AccessionOrder.PatientDisplayName + " (" + this.m_PanelSetOrderLynchSyndromeEvaluation.ReportNo + ")";
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(this.m_PanelSetOrderLynchSyndromeEvaluation.OrderedOnId);
YellowstonePathology.Business.Test.AliquotOrder aliquotOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(this.m_PanelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.m_OrderedOnDescription = specimenOrder.Description;
if (aliquotOrder != null)
{
this.m_OrderedOnDescription += ": " + aliquotOrder.Label;
}
InitializeComponent();
DataContext = this;
this.Loaded += new RoutedEventHandler(LynchSyndromeEvaluationResultPage_Loaded);
}
public LynchSyndromeEvaluationResultPage(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.Business.User.SystemIdentity systemIdentity,
System.Windows.Visibility backButtonVisibility)
: base(panelSetOrderLynchSyndromeEvaluation, accessionOrder)
{
this.m_PanelSetOrderLynchSyndromeEvaluation = panelSetOrderLynchSyndromeEvaluation;
this.m_AccessionOrder = accessionOrder;
this.m_SystemIdentity = systemIdentity;
this.m_BackButtonVisibility = backButtonVisibility;
this.m_LSETypeCollection = new Business.Test.LynchSyndrome.LSETypeCollection();
this.m_PageHeaderText = "Lynch Syndrome Evaluation Results For: " + this.m_AccessionOrder.PatientDisplayName + " (" + this.m_PanelSetOrderLynchSyndromeEvaluation.ReportNo + ")";
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrderByOrderTarget(this.m_PanelSetOrderLynchSyndromeEvaluation.OrderedOnId);
YellowstonePathology.Business.Test.AliquotOrder aliquotOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetAliquotOrder(this.m_PanelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.m_OrderedOnDescription = specimenOrder.Description;
if (aliquotOrder != null) this.m_OrderedOnDescription += ": " + aliquotOrder.Label;
InitializeComponent();
DataContext = this;
this.Loaded += new RoutedEventHandler(LynchSyndromeEvaluationResultPage_Loaded);
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonBack);
this.m_ControlsNotDisabledOnFinal.Add(this.ButtonNext);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockShowDocument);
this.m_ControlsNotDisabledOnFinal.Add(this.TextBlockUnfinalResults);
}
public override void SetResults(AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
{
panelSetOrderLynchSyndromEvaluation.Interpretation = this.m_Interpretation;
panelSetOrderLynchSyndromEvaluation.Comment = this.m_Comment;
panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated = this.m_BRAFIsIndicated;
panelSetOrderLynchSyndromEvaluation.Method = "IHC: " + IHCMethod;
panelSetOrderLynchSyndromEvaluation.References = "IHC: " + LSEGYNReferences;
}
public override void SetResults(AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
{
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderLynchSyndromEvaluation.Interpretation = this.m_Interpretation;
panelSetOrderLynchSyndromEvaluation.Comment = this.m_Comment;
panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated = this.m_BRAFIsIndicated;
panelSetOrderLynchSyndromEvaluation.Method = "IHC: " + IHCMethod + Environment.NewLine + Environment.NewLine + "MLH1: " + panelSetOrderMLH1MethylationAnalysis.Method;
panelSetOrderLynchSyndromEvaluation.References = "IHC: " + LSEGYNReferences + Environment.NewLine + Environment.NewLine + "MLH1: " + panelSetOrderMLH1MethylationAnalysis.References;
}
public LynchSyndromeEvaluationResultPath(string reportNo,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.UI.Navigation.PageNavigator pageNavigator,
System.Windows.Window window,
System.Windows.Visibility backButtonVisibility)
: base(pageNavigator, window)
{
this.m_AccessionOrder = accessionOrder;
this.m_PanelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
this.m_BackButtonVisibility = backButtonVisibility;
}
public LynchSyndromeEvaluationResultPath(string reportNo,
YellowstonePathology.Business.Test.AccessionOrder accessionOrder,
YellowstonePathology.UI.Navigation.PageNavigator pageNavigator,
System.Windows.Window window,
System.Windows.Visibility backButtonVisibility)
: base(pageNavigator, window)
{
this.m_AccessionOrder = accessionOrder;
this.m_PanelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
this.m_BackButtonVisibility = backButtonVisibility;
}
public bool IncludeInIndicationCollection(YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
bool result = false;
if (panelSetOrderLynchSyndromeEvaluation.LynchSyndromeEvaluationType == LSEType.NOTSET)
{
result = true;
}
else if (this.m_Indication == panelSetOrderLynchSyndromeEvaluation.LynchSyndromeEvaluationType)
{
result = true;
}
return(result);
}
public virtual bool MethIsRequired(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
return(false);
}
protected Rules.MethodResult HasFinalBRAFResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
Rules.MethodResult result = new Rules.MethodResult();
result.Success = false;
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTest brafMutationAnalysisTest = new BRAFMutationAnalysis.BRAFMutationAnalysisTest();
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest rasRAFPanelTest = new YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderBraf.Final == true)
{
result.Success = true;
result.Message = panelSetOrderBraf.GetSummaryResult();
}
else
{
result.Success = false;
result.Message = "Unable to set results as the " + brafV600EKTest.PanelSetName + " is not final.";
}
}
else if (accessionOrder.PanelSetOrderCollection.Exists(brafMutationAnalysisTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTestOrder brafMutationAnalysisTestOrder = (YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafMutationAnalysisTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (brafMutationAnalysisTestOrder.Final == true)
{
result.Success = true;
result.Message = brafMutationAnalysisTestOrder.GetSummaryResult();
}
else
{
result.Success = false;
result.Message = "Unable to set results as the " + brafMutationAnalysisTest.PanelSetName + " is not final.";
}
}
else if (accessionOrder.PanelSetOrderCollection.Exists(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder panelSetOrderRASRAF = (YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderRASRAF.Final == true)
{
result.Success = true;
result.Message = panelSetOrderRASRAF.GetBrafSummaryResult();
}
else
{
result.Success = false;
result.Message = "Unable to set results as the " + rasRAFPanelTest.PanelSetName + " is not final.";
}
}
if (result.Success == false && string.IsNullOrEmpty(result.Message) == true)
{
result.Message = "Unable to set results as a BRAF has not been ordered.";
}
return(result);
}
protected Rules.MethodResult HasFinalMethResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
Rules.MethodResult result = new Rules.MethodResult();
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderMLH1MethylationAnalysis.Final == true)
{
result.Success = true;
result.Message = panelSetOrderMLH1MethylationAnalysis.GetSummaryResult();
}
else
{
result.Success = false;
result.Message = "Unable to set results as the " + panelSetMLH1.PanelSetName + " is not final.";
}
}
else
{
result.Success = false;
result.Message = "Unable to set results as a " + panelSetMLH1.PanelSetName + " has not been ordered.";
}
return(result);
}
public virtual Audit.Model.AuditResult IsOkToSetResults(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
Audit.Model.AuditResult result = panelSetOrderLynchSyndromeEvaluation.IsOkToSetResults();
if (result.Status == Audit.Model.AuditStatusEnum.OK)
{
Rules.MethodResult hasIHCResult = this.HasFinalIHCResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
if (hasIHCResult.Success == false)
{
result.Status = Audit.Model.AuditStatusEnum.Failure;
result.Message = hasIHCResult.Message;
}
}
return(result);
}
protected Rules.MethodResult HasFinalIHCResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
Rules.MethodResult result = new Rules.MethodResult();
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderLynchSyndromeIHC.Final == false)
{
result.Success = false;
result.Message = "Unable to set results as the " + panelSetLynchSyndromeIHCPanel.PanelSetName + " is not final.";
}
}
else
{
result.Success = false;
result.Message = "Unable to set results as a " + panelSetLynchSyndromeIHCPanel.PanelSetName + " must be ordered.";
}
return(result);
}
public override void SetResults(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
string result = this.BuildLossResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
result += this.BuildBRAFResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
result += this.BuildMethResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
panelSetOrderLynchSyndromeEvaluation.Result = result;
panelSetOrderLynchSyndromeEvaluation.Interpretation = this.BuildInterpretation(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
panelSetOrderLynchSyndromeEvaluation.Method = this.BuildMethod(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
panelSetOrderLynchSyndromeEvaluation.ReportReferences = LSEColonReferences;
panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth = true;
}
public override void ToXml(XElement document)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_ReportNo);
this.AddHeader(document, panelSetOrderLynchSyndromeEvaluation, "Lynch Syndrome Evaluation");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Interpretation:", document, "F");
this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.Interpretation, document, "F");
this.AddNextObxElement("", document, "F");
this.HandleLongString("Comment:", document, "F");
this.AddNextObxElement(panelSetOrderLynchSyndromeEvaluation.Comment, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Pathologist: " + panelSetOrderLynchSyndromeEvaluation.Signature, document, "F");
if (panelSetOrderLynchSyndromeEvaluation.FinalTime.HasValue == true)
{
this.AddNextObxElement("E-signed " + panelSetOrderLynchSyndromeEvaluation.FinalTime.Value.ToString("MM/dd/yyyy HH:mm"), document, "F");
}
this.AddNextObxElement("", document, "F");
this.AddAmendments(document);
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderLynchSyndromeIHC != null)
{
this.AddNextObxElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document, "F");
this.AddNextObxElement("MLH1: " + panelSetOrderLynchSyndromeIHC.MLH1Result, document, "F");
this.AddNextObxElement("MSH2: " + panelSetOrderLynchSyndromeIHC.MSH2Result, document, "F");
this.AddNextObxElement("MSH6: " + panelSetOrderLynchSyndromeIHC.MSH6Result, document, "F");
this.AddNextObxElement("PMS2: " + panelSetOrderLynchSyndromeIHC.PMS2Result, document, "F");
this.AddNextObxElement("", document, "F");
}
if (panelSetOrderLynchSyndromeEvaluation.BRAFIsIndicated == true)
{
this.AddNextObxElement("Molecular Analysis", document, "F");
this.AddNextObxElement("", document, "F");
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(18) == true) //BRAF
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
this.AddNextObxElement("BRAF V600E Mutation by PCR: " + panelSetOrderBraf.ReportNo, document, "F");
this.AddNextObxElement("Result: " + panelSetOrderBraf.Result, document, "F");
this.AddNextObxElement("", document, "F");
}
}
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.AddNextObxElement("Specimem: " + specimenOrder.Description, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Method: ", document, "F");
this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.Method, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("References: ", document, "F");
this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.References, document, "F");
this.AddNextObxElement("", document, "F");
}
protected string BuildLossResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
string result = null;
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
result = "Loss of nuclear expression of ";
List <string> results = new List <string>();
if (panelSetOrderLynchSyndromeIHC.MLH1Result == LSEIHCResult.LossDescription)
{
results.Add("MLH1");
}
if (panelSetOrderLynchSyndromeIHC.MSH2Result == LSEIHCResult.LossDescription)
{
results.Add("MSH2");
}
if (panelSetOrderLynchSyndromeIHC.MSH6Result == LSEIHCResult.LossDescription)
{
results.Add("MSH6");
}
if (panelSetOrderLynchSyndromeIHC.PMS2Result == LSEIHCResult.LossDescription)
{
results.Add("PMS2");
}
var joinedResults = string.Join(", ", results);
if (results.Count > 1)
{
int posOfLastComma = joinedResults.LastIndexOf(",");
joinedResults = joinedResults.Remove(posOfLastComma, 1);
joinedResults = joinedResults.Insert(posOfLastComma, " and");
}
string multiLoss = "proteins. ";
if (results.Count == 1)
{
multiLoss = "protein. ";
}
result = result + joinedResults + " mismatch repair " + multiLoss;
}
return(result);
}
public override bool MethIsRequired(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
bool result = false;
Rules.MethodResult brafResult = this.HasFinalBRAFResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
if (brafResult.Success == true && brafResult.Message == TestResult.NotDetected)
{
Rules.MethodResult methodResult = this.HasFinalMethResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
if (methodResult.Success == false && methodResult.Message.Contains("has not been ordered") == true)
{
result = true;
}
}
return(result);
}
public override void ToXml(XElement document)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_ReportNo);
this.AddHeader(document, panelSetOrderLynchSyndromeEvaluation, "Mismatch Repair (MMR)/Lynch Syndrome Evaluation");
this.AddNextObxElement("", document, "F");
this.HandleLongString("Result:", document, "F");
this.AddNextObxElement(panelSetOrderLynchSyndromeEvaluation.Result, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Interpretation:", document, "F");
this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.Interpretation, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Pathologist: " + panelSetOrderLynchSyndromeEvaluation.Signature, document, "F");
if (panelSetOrderLynchSyndromeEvaluation.FinalTime.HasValue == true)
{
this.AddNextObxElement("E-signed " + panelSetOrderLynchSyndromeEvaluation.FinalTime.Value.ToString("MM/dd/yyyy HH:mm"), document, "F");
}
this.AddNextObxElement("", document, "F");
this.AddAmendments(document);
LynchSyndromeIHCPanelTest lynchSyndromeIHCPanelTest = new LynchSyndromeIHCPanelTest();
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(lynchSyndromeIHCPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (PanelSetOrderLynchSyndromeIHC)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(lynchSyndromeIHCPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
this.AddNextObxElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document, "F");
this.AddNextObxElement("MLH1: " + panelSetOrderLynchSyndromeIHC.MLH1Result, document, "F");
this.AddNextObxElement("PMS2: " + panelSetOrderLynchSyndromeIHC.PMS2Result, document, "F");
this.AddNextObxElement("MSH2: " + panelSetOrderLynchSyndromeIHC.MSH2Result, document, "F");
this.AddNextObxElement("MSH6: " + panelSetOrderLynchSyndromeIHC.MSH6Result, document, "F");
this.AddNextObxElement("", document, "F");
}
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest rasRAFPanelTest = new YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest();
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (((this.m_AccessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true ||
this.m_AccessionOrder.PanelSetOrderCollection.Exists(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true) &&
panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth == true) ||
this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
this.AddNextObxElement("Molecular Analysis", document, "F");
this.AddNextObxElement("", document, "F");
}
if (panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth == true)
{
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
this.AddNextObxElement("BRAF V600E Mutation by PCR: " + panelSetOrderBraf.ReportNo, document, "F");
this.AddNextObxElement("Result: " + panelSetOrderBraf.Result, document, "F");
this.AddNextObxElement("", document, "F");
}
else if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
{
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder panelSetOrderRASRAF = (YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
this.AddNextObxElement("BRAF V600E Mutation by PCR: " + panelSetOrderRASRAF.ReportNo, document, "F");
this.AddNextObxElement("Result: " + panelSetOrderRASRAF.BRAFResult, document, "F");
this.AddNextObxElement("", document, "F");
}
}
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
this.AddNextObxElement("MLH1 Methylation Analysis: " + panelSetOrderMLH1MethylationAnalysis.ReportNo, document, "F");
this.AddNextObxElement("Result: " + panelSetOrderMLH1MethylationAnalysis.Result, document, "F");
this.AddNextObxElement("", document, "F");
}
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.AddNextObxElement("Specimen: " + specimenOrder.Description, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("Method: ", document, "F");
this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.Method, document, "F");
this.AddNextObxElement("", document, "F");
this.AddNextObxElement("References: ", document, "F");
this.HandleLongString(panelSetOrderLynchSyndromeEvaluation.ReportReferences, document, "F");
this.AddNextObxElement("", document, "F");
string asr = "This test was developed and its performance characteristics determined by Yellowstone Pathology Institute, Inc. It has not been cleared or approved by the U.S. Food and Drug Administration. The FDA has determined that such clearance or approval is not necessary. This test is used for clinical purposes. It should not be regarded as investigational or for research. This laboratory is certified under the Clinical Laboratory Improvement Amendments of 1988 (CLIA-88) as qualified to perform high complexity clinical laboratory testing.";
this.AddNextObxElement(asr, document, "F");
this.AddNextObxElement("", document, "F");
LynchSyndromeEvaluationTest lynchSyndromeEvaluationTest = new LynchSyndromeEvaluationTest();
string peformedAtLocation = this.m_AccessionOrder.PanelSetOrderCollection.GetLocationPerformedSummary(lynchSyndromeEvaluationTest.PanelSetIDList);
this.HandleLongString(peformedAtLocation, document, "F");
this.AddNextObxElement("", document, "F");
}
public override void Render()
{
int molecularTestCount = 0;
this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\LynchSyndromeEvaluation.6.xml";
this.OpenTemplate();
this.SetDemographicsV2();
this.SetReportDistribution();
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_PanelSetOrder;
base.ReplaceText("report_interpretation", panelSetOrderLynchSyndromeEvaluation.Interpretation);
base.ReplaceText("report_comment", panelSetOrderLynchSyndromeEvaluation.Comment);
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.ReplaceText("specimen_description", specimenOrder.Description);
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
if (panelSetOrderLynchSyndromeIHC != null)
{
base.ReplaceText("mlh1_result", panelSetOrderLynchSyndromeIHC.MLH1Result);
base.ReplaceText("msh2_result", panelSetOrderLynchSyndromeIHC.MSH2Result);
base.ReplaceText("msh6_result", panelSetOrderLynchSyndromeIHC.MSH6Result);
base.ReplaceText("pms2_result", panelSetOrderLynchSyndromeIHC.PMS2Result);
}
if (panelSetOrderLynchSyndromeEvaluation.BRAFIsIndicated == true)
{
molecularTestCount += 1;
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(18) == true) //BRAF
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId);
base.ReplaceText("braf_result", panelSetOrderBraf.Result);
base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
}
}
else
{
this.DeleteRow("braf_result");
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId) == true)
{
molecularTestCount += 1;
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId);
base.ReplaceText("mlh1methylation_result", panelSetOrderMLH1MethylationAnalysis.Result);
base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
}
else
{
this.DeleteRow("mlh1methylation_result");
}
if (molecularTestCount == 0)
{
this.DeleteRow("molecular_analysis_header");
}
base.ReplaceText("report_references", panelSetOrderLynchSyndromeEvaluation.References);
base.ReplaceText("report_method", panelSetOrderLynchSyndromeEvaluation.Method);
base.ReplaceText("pathologist_signature", panelSetOrderLynchSyndromeEvaluation.Signature);
this.SaveReport();
}
public virtual void SetResults(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
{
panelSetOrderLynchSyndromEvaluation.Interpretation = this.m_Interpretation;
panelSetOrderLynchSyndromEvaluation.Comment = this.m_Comment;
panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated = this.m_BRAFIsIndicated;
panelSetOrderLynchSyndromEvaluation.Method = this.m_Method;
panelSetOrderLynchSyndromEvaluation.References = this.m_References;
}
public static LSEResult GetResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromEvaluation)
{
LSEResult result = new LSEResult();
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId);
if (panelSetOrderLynchSyndromeIHC != null)
{
panelSetOrderLynchSyndromeIHC.SetSummaryResult(result);
}
if (panelSetOrderLynchSyndromEvaluation.BRAFIsIndicated == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderBraf.SetSummaryResult(result);
}
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromEvaluation.OrderedOnId, true);
panelSetOrderMLH1MethylationAnalysis.SetSummaryResult(result);
}
return(result);
}
public override void SetResults(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
panelSetOrderLynchSyndromeEvaluation.Result = LSERule.IHCAllIntactResult;
panelSetOrderLynchSyndromeEvaluation.Interpretation = LSEGYNAllIntact.Interpretation;
panelSetOrderLynchSyndromeEvaluation.Method = IHCMethod;
panelSetOrderLynchSyndromeEvaluation.ReportReferences = LSEGYNReferences;
panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth = false;
}
public virtual void SetResults(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
throw new Exception("SetResults Not implemented in LSERule.");
}
public override void SetResults(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
panelSetOrderLynchSyndromeEvaluation.Result = this.BuildLossResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
panelSetOrderLynchSyndromeEvaluation.Interpretation = LSEColonSendOut.Interpretation;
panelSetOrderLynchSyndromeEvaluation.Method = IHCMethod;
panelSetOrderLynchSyndromeEvaluation.ReportReferences = LSEColonReferences;
panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth = false;
}
public override void ToXml(XElement document)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrder = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(106);
this.AddCompanyHeader(document);
this.AddBlankNteElement(document);
this.AddNextNteElement("Lynch Syndrome Evaluation", document);
this.AddNextNteElement("Master Accession #: " + panelSetOrder.MasterAccessionNo, document);
this.AddNextNteElement("Report #: " + panelSetOrder.ReportNo, document);
this.AddBlankNteElement(document);
this.AddNextNteElement("Interpretation: ", document);
this.HandleLongString(panelSetOrder.Interpretation, document);
this.AddBlankNteElement(document);
this.AddNextNteElement("Comment: ", document);
this.HandleLongString(panelSetOrder.Comment, document);
this.AddBlankNteElement(document);
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102);
if (panelSetOrderLynchSyndromeIHC != null)
{
this.AddNextNteElement("Mismatch Repair Protein Expression by Immunohistochemistry: ", document);
this.AddNextNteElement("MLH1: " + panelSetOrderLynchSyndromeIHC.MLH1Result, document);
this.AddNextNteElement("MSH2: " + panelSetOrderLynchSyndromeIHC.MSH2Result, document);
this.AddNextNteElement("MSH6: " + panelSetOrderLynchSyndromeIHC.MSH6Result, document);
this.AddNextNteElement("PMS2: " + panelSetOrderLynchSyndromeIHC.PMS2Result, document);
this.AddBlankNteElement(document);
}
if (panelSetOrder.BRAFIsIndicated == true)
{
this.AddNextNteElement("Molecular Analysis", document);
this.AddBlankNteElement(document);
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(18) == true) //BRAF
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId);
this.AddNextNteElement("BRAF V600E Mutation by PCR: " + panelSetOrderBraf.ReportNo, document);
this.AddNextNteElement("Result: " + panelSetOrderBraf.Result, document);
this.AddBlankNteElement(document);
}
}
this.AddNextNteElement("Method: ", document);
this.HandleLongString(panelSetOrder.Method, document);
this.AddBlankNteElement(document);
this.AddNextNteElement("References: ", document);
this.HandleLongString(panelSetOrder.References, document);
this.AddBlankNteElement(document);
}
private string BuildInterpretation(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
string result = LSEColonBRAFMeth.Interpretation;
Rules.MethodResult brafResult = this.HasFinalBRAFResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
Rules.MethodResult methResult = this.HasFinalMethResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
if (brafResult.Message == TestResult.NotDetected && methResult.Message == TestResult.NotDetected)
{
result = BRAFMethNotDetectedInterpretation;
}
return(result);
}
private static LSERuleCollection GetIHCCollection(LSERuleCollection lseRuleCollection, YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
LSERuleCollection result = new LSERuleCollection();
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest panelSetLynchSyndromeIHCPanel = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeIHCPanelTest();
foreach (LSERule lseRule in lseRuleCollection)
{
if (accessionOrder.PanelSetOrderCollection.Exists(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLynchSyndromeIHCPanel.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderLynchSyndromeIHC.Final == true)
{
if (lseRule.IncludeInIHCCollection(panelSetOrderLynchSyndromeIHC) == true)
{
result.Add(lseRule);
}
}
else
{
result.Add(lseRule);
}
}
else
{
result.Add(lseRule);
}
}
return(result);
}
protected string BuildMethResult(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
string result = string.Empty;
Rules.MethodResult methResult = this.HasFinalMethResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
if (methResult.Success == true)
{
result = Environment.NewLine + "MLH1 promoter methylation " + methResult.Message.ToUpper();
}
return(result);
}
public override void Run()
{
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeEvaluationTest panelSetLSE = new YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeEvaluationTest();
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetLSE.PanelSetId) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLSE = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetLSE.PanelSetId);
if (panelSetOrderLSE.LynchSyndromeEvaluationType == YellowstonePathology.Business.Test.LynchSyndrome.LSEType.NOTSET)
{
this.m_ActionRequired = true;
this.m_Message.AppendLine("The Lynch Syndrome Evaluation Type is not set.");
}
}
}
protected string BuildMethod(YellowstonePathology.Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation)
{
string result = string.Empty;
Rules.MethodResult brafResult = this.HasFinalBRAFResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
Rules.MethodResult methResult = this.HasFinalMethResult(accessionOrder, panelSetOrderLynchSyndromeEvaluation);
if (brafResult.Success == true && methResult.Success == true)
{
result = IHCBRAFMLHMethod;
}
else if (brafResult.Success == true && methResult.Success == false)
{
result = IHCBRAFMethod;
}
else if (brafResult.Success == false && methResult.Success == true)
{
result = IHCMLHMethod;
}
else
{
result = IHCMethod;
}
return(result);
}
public override void Run()
{
this.m_Status = AuditStatusEnum.OK;
YellowstonePathology.Business.Test.ComprehensiveColonCancerProfile.ComprehensiveColonCancerProfileTest comprehensiveColonCancerProfileTest = new Test.ComprehensiveColonCancerProfile.ComprehensiveColonCancerProfileTest();
YellowstonePathology.Business.Test.LynchSyndrome.LynchSyndromeEvaluationTest lynchSyndromeEvaluationTest = new Test.LynchSyndrome.LynchSyndromeEvaluationTest();
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(lynchSyndromeEvaluationTest.PanelSetId) == true)
{
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(lynchSyndromeEvaluationTest.PanelSetId);
if (panelSetOrderLynchSyndromeEvaluation.LynchSyndromeEvaluationType == YellowstonePathology.Business.Test.LynchSyndrome.LSEType.COLON)
{
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(comprehensiveColonCancerProfileTest.PanelSetId) == false)
{
this.m_Status = AuditStatusEnum.Warning;
this.m_Message.AppendLine("This case may benefit from a Comprehensive Colon Cancer Profile. Click YES if you would like to stop and order one or click NO to continue without ordering one.");
}
}
}
}
public override void Render()
{
Business.Test.LynchSyndrome.LynchSyndromeEvaluationTest lynchSyndromeEvaluationTest = new LynchSyndromeEvaluationTest();
int molecularTestCount = 0;
this.m_TemplateName = @"\\CFileServer\Documents\ReportTemplates\XmlTemplates\LynchSyndromeEvaluation.2.xml";
this.OpenTemplate();
this.SetDemographicsV2();
this.SetReportDistribution();
YellowstonePathology.Business.Amendment.Model.AmendmentCollection amendmentCollection = this.m_AccessionOrder.AmendmentCollection.GetAmendmentsForReport(m_PanelSetOrder.ReportNo);
this.SetAmendments(amendmentCollection);
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation panelSetOrderLynchSyndromeEvaluation = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeEvaluation) this.m_PanelSetOrder;
base.ReplaceText("report_result", panelSetOrderLynchSyndromeEvaluation.Result);
base.ReplaceText("report_interpretation", panelSetOrderLynchSyndromeEvaluation.Interpretation);
YellowstonePathology.Business.Specimen.Model.SpecimenOrder specimenOrder = this.m_AccessionOrder.SpecimenOrderCollection.GetSpecimenOrder(panelSetOrderLynchSyndromeEvaluation.OrderedOn, panelSetOrderLynchSyndromeEvaluation.OrderedOnId);
this.ReplaceText("specimen_description", specimenOrder.Description);
string collectionDateTimeString = YellowstonePathology.Business.Helper.DateTimeExtensions.CombineDateAndTime(specimenOrder.CollectionDate, specimenOrder.CollectionTime);
this.SetXmlNodeData("date_time_collected", collectionDateTimeString);
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC panelSetOrderLynchSyndromeIHC = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderLynchSyndromeIHC) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(102, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
if (panelSetOrderLynchSyndromeIHC != null)
{
base.ReplaceText("mlh1_result", panelSetOrderLynchSyndromeIHC.MLH1Result);
base.ReplaceText("msh2_result", panelSetOrderLynchSyndromeIHC.MSH2Result);
base.ReplaceText("msh6_result", panelSetOrderLynchSyndromeIHC.MSH6Result);
base.ReplaceText("pms2_result", panelSetOrderLynchSyndromeIHC.PMS2Result);
}
if (panelSetOrderLynchSyndromeEvaluation.ReflexToBRAFMeth == true)
{
molecularTestCount += 1;
YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTest brafMutationAnlaysis = new BRAFMutationAnalysis.BRAFMutationAnalysisTest();
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest();
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest rasRAFPanelTest = new YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTest();
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
base.ReplaceText("braf_result", panelSetOrderBraf.Result);
base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
}
else if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(brafMutationAnlaysis.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
{
YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTestOrder panelSetOrderBraf = (YellowstonePathology.Business.Test.BRAFMutationAnalysis.BRAFMutationAnalysisTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafMutationAnlaysis.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
base.ReplaceText("braf_result", panelSetOrderBraf.Result);
base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
}
else if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false) == true)
{
YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder panelSetOrderRASRAF = (YellowstonePathology.Business.Test.RASRAFPanel.RASRAFPanelTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(rasRAFPanelTest.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, false);
base.ReplaceText("braf_result", panelSetOrderRASRAF.BRAFResult);
base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
}
}
else
{
this.DeleteRow("braf_result");
}
YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest panelSetMLH1 = new YellowstonePathology.Business.Test.LynchSyndrome.MLH1MethylationAnalysisTest();
if (this.m_AccessionOrder.PanelSetOrderCollection.Exists(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true) == true)
{
molecularTestCount += 1;
YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis panelSetOrderMLH1MethylationAnalysis = (YellowstonePathology.Business.Test.LynchSyndrome.PanelSetOrderMLH1MethylationAnalysis) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(panelSetMLH1.PanelSetId, panelSetOrderLynchSyndromeEvaluation.OrderedOnId, true);
base.ReplaceText("mlh1methylation_result", panelSetOrderMLH1MethylationAnalysis.Result);
base.ReplaceText("molecular_analysis_header", "Molecular Analysis");
}
else
{
this.DeleteRow("mlh1methylation_result");
}
if (molecularTestCount == 0)
{
this.DeleteRow("molecular_analysis_header");
}
base.ReplaceText("report_references", panelSetOrderLynchSyndromeEvaluation.ReportReferences);
base.ReplaceText("report_method", panelSetOrderLynchSyndromeEvaluation.Method);
base.ReplaceText("pathologist_signature", panelSetOrderLynchSyndromeEvaluation.Signature);
base.ReplaceText("summary_location_performed", this.m_AccessionOrder.PanelSetOrderCollection.GetLocationPerformedSummary(lynchSyndromeEvaluationTest.PanelSetIDList));
this.SaveReport();
}
