public KRASStandardReflexKRASOnlyResult(string reportNo, Business.Test.AccessionOrder accessionOrder)
: base(reportNo, accessionOrder)
{
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest krasStandardTest = new KRASStandard.KRASStandardTest();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder krasStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(krasStandardTest.PanelSetId, this.KRASStandardReflexTestOrder.OrderedOnId, true);
this.m_KRASStandardResult = krasStandardTestOrder.Result;
if (krasStandardTestOrder.Final == true)
{
this.m_KRASStandardResult = krasStandardTestOrder.Result;
YellowstonePathology.Business.Test.KRASStandard.KRASStandardNotDetectedResult notDetectedResult = new KRASStandard.KRASStandardNotDetectedResult();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardDetectedResult detectedResult = new KRASStandard.KRASStandardDetectedResult();
if (krasStandardTestOrder.ResultCode == detectedResult.ResultCode)
{
this.m_KRASStandardMutationDetected = this.m_KRASStandardTestOrder.MutationDetected;
this.m_BRAFV600EKResult = KRASStandardReflexResult.NotClinicallyIndicatedResult;
this.m_KRASStandardResult = this.m_KRASStandardResult + " - " + this.m_KRASStandardMutationDetected;
}
else
{
this.m_BRAFV600EKResult = KRASStandardReflexResult.NotOrderedResult;
}
}
else
{
this.m_KRASStandardResult = KRASStandardReflexResult.PendingResult;
this.m_BRAFV600EKResult = KRASStandardReflexResult.PendingResult;
}
}
public KRASStandardReflexKRASOnlyResult(string reportNo, Business.Test.AccessionOrder accessionOrder) : base(reportNo, accessionOrder)
{
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest krasStandardTest = new KRASStandard.KRASStandardTest();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder krasStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(krasStandardTest.PanelSetId, this.KRASStandardReflexTestOrder.OrderedOnId, true);
this.m_KRASStandardResult = krasStandardTestOrder.Result;
if (krasStandardTestOrder.Final == true)
{
this.m_KRASStandardResult = krasStandardTestOrder.Result;
YellowstonePathology.Business.Test.KRASStandard.KRASStandardNotDetectedResult notDetectedResult = new KRASStandard.KRASStandardNotDetectedResult();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardDetectedResult detectedResult = new KRASStandard.KRASStandardDetectedResult();
if (krasStandardTestOrder.ResultCode == detectedResult.ResultCode)
{
this.m_KRASStandardMutationDetected = this.m_KRASStandardTestOrder.MutationDetected;
this.m_BRAFV600EKResult = KRASStandardReflexResult.NotClinicallyIndicatedResult;
this.m_KRASStandardResult = this.m_KRASStandardResult + " - " + this.m_KRASStandardMutationDetected;
}
else
{
this.m_BRAFV600EKResult = KRASStandardReflexResult.NotOrderedResult;
}
}
else
{
this.m_KRASStandardResult = KRASStandardReflexResult.PendingResult;
this.m_BRAFV600EKResult = KRASStandardReflexResult.PendingResult;
}
}
public override void OrderInitialTests(Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Interface.IOrderTarget orderTarget)
{
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest krasStandardTest = new KRASStandard.KRASStandardTest();
if (accessionOrder.PanelSetOrderCollection.Exists(krasStandardTest.PanelSetId, orderTarget.GetId(), true) == false)
{
YellowstonePathology.Business.Test.TestOrderInfo testOrderInfo = new Business.Test.TestOrderInfo(krasStandardTest, orderTarget, true);
YellowstonePathology.Business.Visitor.OrderTestOrderVisitor orderTestOrderVisitor = new Business.Visitor.OrderTestOrderVisitor(testOrderInfo);
accessionOrder.TakeATrip(orderTestOrderVisitor);
}
}
public KRASStandardReflexResult(string reportNo, Business.Test.AccessionOrder accessionOrder)
{
this.m_AccessionOrder = accessionOrder;
this.m_KRASStandardReflexTest = new KRASStandardReflexTest();
this.m_KRASStandardReflexTestOrder = (YellowstonePathology.Business.Test.KRASStandardReflex.KRASStandardReflexTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
this.m_KRASStandardTest = new KRASStandard.KRASStandardTest();
this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, this.m_KRASStandardReflexTestOrder.OrderedOnId, true);
this.m_BRAFV600EKTest = new BRAFV600EK.BRAFV600EKTest();
this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder) this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, this.m_KRASStandardReflexTestOrder.OrderedOn, true);
this.m_References = "1. Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol. 2008; 26(10): 1626-1634. " +
"2. Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res. 2007; 67(6): 2643-2648.";
}
public KRASStandardReflexResult(string reportNo, Business.Test.AccessionOrder accessionOrder)
{
this.m_AccessionOrder = accessionOrder;
this.m_KRASStandardReflexTest = new KRASStandardReflexTest();
this.m_KRASStandardReflexTestOrder = (YellowstonePathology.Business.Test.KRASStandardReflex.KRASStandardReflexTestOrder)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
this.m_KRASStandardTest = new KRASStandard.KRASStandardTest();
this.m_KRASStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_KRASStandardTest.PanelSetId, this.m_KRASStandardReflexTestOrder.OrderedOnId, true);
this.m_BRAFV600EKTest = new BRAFV600EK.BRAFV600EKTest();
this.m_BRAFV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)this.m_AccessionOrder.PanelSetOrderCollection.GetPanelSetOrder(this.m_BRAFV600EKTest.PanelSetId, this.m_KRASStandardReflexTestOrder.OrderedOn, true);
this.m_References = "1. Amado RG, Wolf M, Peeters M, et al. Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer. J Clin Oncol. 2008; 26(10): 1626-1634. " +
"2. Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res. 2007; 67(6): 2643-2648.";
}
public static KRASStandardReflexResult GetResult(string reportNo, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
{
KRASStandardReflexResult result = null;
YellowstonePathology.Business.Test.KRASStandardReflex.KRASStandardReflexTestOrder krasStandardReflexTestOrder = (YellowstonePathology.Business.Test.KRASStandardReflex.KRASStandardReflexTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest krasStandardTest = new KRASStandard.KRASStandardTest();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder krasStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(krasStandardTest.PanelSetId, krasStandardReflexTestOrder.OrderedOnId, true);
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, krasStandardReflexTestOrder.OrderedOnId, true) == false)
{
result = new KRASStandardReflexKRASOnlyResult(reportNo, accessionOrder);
}
else
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder brafV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, krasStandardReflexTestOrder.OrderedOnId, true);
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKNotDetectedResult brafV600EKNotDetectedResult = new BRAFV600EK.BRAFV600EKNotDetectedResult();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardNotDetectedResult krasStandardNotDetectedResult = new KRASStandard.KRASStandardNotDetectedResult();
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKDetectedResult brafV600EKDetectedResult = new BRAFV600EK.BRAFV600EKDetectedResult();
if (krasStandardTestOrder.ResultCode == krasStandardNotDetectedResult.ResultCode &&
brafV600EKTestOrder.ResultCode == brafV600EKNotDetectedResult.ResultCode)
{
result = new KRASStandardReflexBothNotDetectedResult(reportNo, accessionOrder);
}
else if (krasStandardTestOrder.ResultCode == krasStandardNotDetectedResult.ResultCode &&
brafV600EKTestOrder.ResultCode == brafV600EKDetectedResult.ResultCode)
{
result = new KRASStandardReflexKRASNotDetecedBRAFDetectedResult(reportNo, accessionOrder);
}
else
{
result = new KRASStandardReflexKRASWithBRAFResult(reportNo, accessionOrder);
}
}
return(result);
}
public static KRASStandardReflexResult GetResult(string reportNo, YellowstonePathology.Business.Test.AccessionOrder accessionOrder)
{
KRASStandardReflexResult result = null;
YellowstonePathology.Business.Test.KRASStandardReflex.KRASStandardReflexTestOrder krasStandardReflexTestOrder = (YellowstonePathology.Business.Test.KRASStandardReflex.KRASStandardReflexTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(reportNo);
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest krasStandardTest = new KRASStandard.KRASStandardTest();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder krasStandardTestOrder = (YellowstonePathology.Business.Test.KRASStandard.KRASStandardTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(krasStandardTest.PanelSetId, krasStandardReflexTestOrder.OrderedOnId, true);
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTest brafV600EKTest = new BRAFV600EK.BRAFV600EKTest();
if (accessionOrder.PanelSetOrderCollection.Exists(brafV600EKTest.PanelSetId, krasStandardReflexTestOrder.OrderedOnId, true) == false)
{
result = new KRASStandardReflexKRASOnlyResult(reportNo, accessionOrder);
}
else
{
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder brafV600EKTestOrder = (YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKTestOrder)accessionOrder.PanelSetOrderCollection.GetPanelSetOrder(brafV600EKTest.PanelSetId, krasStandardReflexTestOrder.OrderedOnId, true);
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKNotDetectedResult brafV600EKNotDetectedResult = new BRAFV600EK.BRAFV600EKNotDetectedResult();
YellowstonePathology.Business.Test.KRASStandard.KRASStandardNotDetectedResult krasStandardNotDetectedResult = new KRASStandard.KRASStandardNotDetectedResult();
YellowstonePathology.Business.Test.BRAFV600EK.BRAFV600EKDetectedResult brafV600EKDetectedResult = new BRAFV600EK.BRAFV600EKDetectedResult();
if (krasStandardTestOrder.ResultCode == krasStandardNotDetectedResult.ResultCode &&
brafV600EKTestOrder.ResultCode == brafV600EKNotDetectedResult.ResultCode)
{
result = new KRASStandardReflexBothNotDetectedResult(reportNo, accessionOrder);
}
else if (krasStandardTestOrder.ResultCode == krasStandardNotDetectedResult.ResultCode &&
brafV600EKTestOrder.ResultCode == brafV600EKDetectedResult.ResultCode)
{
result = new KRASStandardReflexKRASNotDetecedBRAFDetectedResult(reportNo, accessionOrder);
}
else
{
result = new KRASStandardReflexKRASWithBRAFResult(reportNo, accessionOrder);
}
}
return result;
}
public override void OrderInitialTests(Business.Test.AccessionOrder accessionOrder, YellowstonePathology.Business.Interface.IOrderTarget orderTarget)
{
YellowstonePathology.Business.Test.KRASStandard.KRASStandardTest krasStandardTest = new KRASStandard.KRASStandardTest();
if (accessionOrder.PanelSetOrderCollection.Exists(krasStandardTest.PanelSetId, orderTarget.GetId(), true) == false)
{
YellowstonePathology.Business.Test.TestOrderInfo testOrderInfo = new Business.Test.TestOrderInfo(krasStandardTest, orderTarget, true);
YellowstonePathology.Business.Visitor.OrderTestOrderVisitor orderTestOrderVisitor = new Business.Visitor.OrderTestOrderVisitor(testOrderInfo);
accessionOrder.TakeATrip(orderTestOrderVisitor);
}
}
